5-Bromo-2-chloro-3-(trifluoromethoxy)pyridine CAS 1361852-60-9
| CAS No. | 1361852-60-9 |
| Molecular Formula | C6H2BrClF3NO |
| Molecular Weight | 276.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Bromo-2-chloro-3-(trifluoromethoxy)pyridine.
CATO supplies 5-Bromo-2-chloro-3-(trifluoromethoxy)pyridine (CAS 1361852-60-9), a certified reference material (molecular formula C6H2BrClF3NO, MW 276.44 g/mol) for analytical method development and quality control.
The molecular framework of 5-Bromo-2-chloro-3-(trifluoromethoxy)pyridine (C6H2BrClF3NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Bromo-2-chloro-3-(trifluoromethoxy)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H2BrClF3NO |
| Molecular Weight | 276.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
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- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
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