1-(5-Bromo-3-nitropyridin-2-yl)ethanone CAS 1363382-81-3
| CAS No. | 1363382-81-3 |
| Molecular Formula | C7H5BrN2O3 |
| Molecular Weight | 245.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(5-Bromo-3-nitropyridin-2-yl)ethanone.
1-(5-Bromo-3-nitropyridin-2-yl)ethanone (CAS 1363382-81-3), molecular formula C7H5BrN2O3 and molecular weight 245.03 g/mol, is a CATO reference standard with documented purity and traceability.
1-(5-Bromo-3-nitropyridin-2-yl)ethanone (C7H5BrN2O3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(5-Bromo-3-nitropyridin-2-yl)ethanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5BrN2O3 |
| Molecular Weight | 245.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 2-Bromo-6-nitrobenzamide (CAS 107485-65-4)
- 4-Bromo-2-nitrobenzamide (CAS 1152237-09-6)
- 2-(4-bromo-2-hydroxyphenyl)-2-oxoacetic acid (CAS 1221724-46-4)
- 3-Bromo-4-nitrobenzamide (CAS 1261794-86-8)
- 1-(6-bromo-4-nitropyridin-2-yl)ethan-1-one (CAS 1393576-45-8)
- 2-Bromo-3-nitrobenzamide (CAS 35757-19-8)
- 2-Bromo-4-nitrobenzamide (CAS 91808-64-9)
- 2-Bromo-5-nitrobenzamide (CAS 41052-26-0)
Recommended Standards
- 1,3-Dichloro-5-methyl-2-(trifluoromethoxy)benzene (CAS 1350760-79-0)
- [3,5-dichloro-4-(trifluoromethyl)phenyl]methanol (CAS 1788733-89-0)
- 4-Chloro-2-(chloromethyl)-1-(trifluoromethoxy)benzene (CAS 1261791-12-1)
- (3,4-Dichloro-5-(trifluoromethyl)phenyl)methanol (CAS 1824048-31-8)
- 1-Isobutyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1267130-56-2)
- (9Z,12E)-Tetradecadien-1-ol Acetate (CAS 30507-70-1)
- (2E)-3-(4-Bromophenyl)-1-(4-methylphenyl)prop-2-en-1-one (CAS 7020-14-6)
- (2e)-3-[4-({4-[(carboxymethyl)carbamoyl]phenyl}sulfamoyl)phenyl]prop-2-enoic acid (CAS 851207-45-9)
- Tris(4-bromo-2,3,5,6-tetramethylphenyl)borane (CAS 321735-68-6)
- 3-(2-(Isopropylamino)-2-oxoethoxy)-2-naphthoic acid (CAS 1016504-35-0)
- N-(3-Chloro-4-methoxyphenyl)-5-methyl-12-oxo-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide (CAS 1775415-48-9)
- 2-(2-Chloroethyl)piperidine (CAS 111781-62-5)
- 5-Isobutoxy-3-methylpentane-1-sulfonyl chloride (CAS 1490938-52-7)
- Neuropeptide VF (124-131) (human) (CAS 311309-27-0)
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