1-((2R,3R,4S)-3,4-Bis(hydroxymethyl)oxetan-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione CAS 136451-98-4
| CAS No. | 136451-98-4 |
| Molecular Formula | C10H14N2O5 |
| Molecular Weight | 242.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-((2R,3R,4S)-3,4-Bis(hydroxymethyl)oxetan-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione (CAS 136451-98-4), molecular formula C10H14N2O5 and molecular weight 242.23 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-((2R,3R,4S)-3,4-Bis(hydroxymethyl)oxetan-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione (C10H14N2O5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 242.23 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14N2O5 |
| Molecular Weight | 242.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 2 |
Recommended Standards
- 3-(1-Methyl-1H-pyrrol-2-yl)[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid (CAS 1353504-92-3)
- 2-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridine-7-carboxylic acid (CAS 1375474-20-6)
- 2-(4-Methoxyphenyl)pyrazolo[1,5-d][1,2,4]triazin-4(5h)-one (CAS 135104-21-1)
- 5-(((tert-Butoxycarbonyl)amino)methyl)isoxazole-3-carboxylic acid (CAS 138742-19-5)
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- 2-((6-(Cyclohexylamino)-9-methyl-9H-purin-2-yl)amino)ethanol (CAS 925254-30-4)
- 2-(5-(Pyrrolidin-2-yl)-1H-1,2,4-triazol-1-yl)pyridine (CAS 1708199-25-0)
- Insulin Degludec Impurity 11 (CAS CATO-C4X-215711)
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