Methyl 3,3'-difluoro-5'-methoxy-[1,1'-biphenyl]-4-carboxylate CAS 1365272-01-0
| CAS No. | 1365272-01-0 |
| Molecular Formula | C15H12F2O3 |
| Molecular Weight | 278.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 3,3'-difluoro-5'-methoxy-[1,1'-biphenyl]-4-carboxylate.
Methyl 3,3'-difluoro-5'-methoxy-[1,1'-biphenyl]-4-carboxylate (CAS 1365272-01-0), molecular formula C15H12F2O3 and molecular weight 278.25 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system, Methyl 3,3'-difluoro-5'-methoxy-[1,1'-biphenyl]-4-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 278.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Methyl 3,3'-difluoro-5'-methoxy-[1,1'-biphenyl]-4-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H12F2O3 |
| Molecular Weight | 278.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
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Recommended Standards
- N-(3-bromophenyl)thian-3-amine (CAS 1343375-65-4)
- Methyl 2-fluoro-4-(5-fluoro-2-methoxyphenyl)benzoate (CAS 1365272-32-7)
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- Methyl 2-fluoro-3-(4-fluoro-3-methoxyphenyl)benzoate (CAS 1381944-46-2)
- 0211AD 1185294-32-9 2-[2-(1-Methyl-1H-imidazol-2-yl)ethyl]-benzoic acid hydrochloride C13H15ClN2O2 (CAS 1185294-32-9)
- Decloxizine (CAS 3733-63-9)
- 9-(4-Aminophenyl)-9H-purin-6-amine (CAS 863675-87-0)
- [1,3]Dioxolo[4,5-b]pyridin-6-amine (CAS 1367946-80-2)
- 1171242-99-1 3-Morpholin-4-yl-3-pyridin-3-ylpropanoic acid MFCD14281845 (CAS 1171242-99-1)
- 2-Chloro-7-(pentan-3-yl)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid (CAS 959799-15-6)
- Ethyl 2-chloro-5-methylphenylacetic acid (CAS 91552-39-5)
- 3-(3-(Hydroxymethyl)pyrrolidin-1-yl)propanoic acid (CAS 1250246-61-7)
- Methyl (3S,6S)-6-methylpiperidine-3-carboxylate (CAS 1009376-90-2)
- Des-Gly34-Tirzepatide (CAS CATO-CPTD788940)
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