[1,3]Dioxolo[4,5-b]pyridin-6-amine CAS 1367946-80-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1367946-80-2
Molecular FormulaC6H6N2O2
Molecular Weight138.12 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

[1,3]Dioxolo[4,5-b]pyridin-6-amine CAS 1367946-80-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including [1,3]Dioxolo[4,5-b]pyridin-6-amine.

[1,3]Dioxolo[4,5-b]pyridin-6-amine (CAS 1367946-80-2) is a high-purity analytical reference standard with the molecular formula C6H6N2O2 and a molecular weight of 138.12 g/mol.

Structurally, [1,3]Dioxolo[4,5-b]pyridin-6-amine (C6H6N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 138.12 g/mol, it falls into the low-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), [1,3]Dioxolo[4,5-b]pyridin-6-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H6N2O2
Molecular Weight138.12 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Nitrogen Atoms2

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