Lamotrigine Impurity 11 CAS CATO-C4X-167211
| CAS No. | CATO-C4X-167211 |
| Molecular Formula | C9H7Cl2N5O |
| Molecular Weight | 272.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lamotrigine Impurity 11.
As a process- or degradation-related impurity, Lamotrigine Impurity 11 (CAS CATO-C4X-167211, C9H7Cl2N5O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Lamotrigine Impurity 11 (C9H7Cl2N5O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H7Cl2N5O |
| Molecular Weight | 272.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Lamotrigine Standards
- Lamotrigine Impurity 13 (CAS CATO-C4X-167213)
- Lamotrigine Impurity 14 (CAS CATO-C4X-167214)
- Lamotrigine impurity 20 (CAS 136565-76-9)
- Lamotrigine impurity 21 (CAS CATO-C4X-167221)
- Lamotrigine-13C3,d3, Major (CAS 1246815-13-3)
- Lamotrigine-d3 (CAS 1132746-94-1)
- Lamotrigine-13C3 (CAS 1188265-38-4)
- Lamotrigine EP Impurity D (CAS 661463-79-2)
Recommended Standards
- methyl 2-(2-bromo-3-pyridyl)-2,2-difluoro-acetate (CAS 2761389-76-6)
- 6,7-Dichloro-3,5-dihydro-1-hydroxyimidazo[1,2-α]quinazolin-2(1H)-one(Anagrelide Impurity) (CAS 875467-41-7)
- 6-((3,4-Dichlorophenyl)amino)pyrimidine-2,4(1H,3H)-dione (CAS 6972-74-3)
- 4-Iodo-5,6-dimethyl-1H-benzo[d]imidazole (CAS 2411789-56-3)
- Isavuconazole Impurity 70 (CAS CATO-C4X-123670)
- Fasudil Impurity 39 (CAS 4403-78-5)
- Domperidone Impurity 28 (CAS CATO-C4X-142028)
- 2-Phenyl-1-(pyridin-3-yl)ethan-1-one (CAS 14627-92-0)
- Diethyl 2-(3-buten-1-yl)-2-methylmalonate (CAS 5331-70-4)
- 3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-6-amine (CAS 1934583-81-9)
- [6-(2-Methoxyethoxy)-5-methylpyridin-3-yl]boronic acid (CAS 2377608-87-0)
- 5-Chloro-4-methyl-N-(2-morpholinoethyl)benzo[d]thiazol-2-amine (CAS 1177328-36-7)
- Synephrine Hydrochloride (CAS 5985-28-4)
- Autoinducing Peptide I trifluoroacetate salt (CAS 200010-29-3)
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