1-(2-Fluorophenyl)-1H-pyrrole-2-carbonitrile CAS 136773-60-9
| CAS No. | 136773-60-9 |
| Molecular Formula | C11H7FN2 |
| Molecular Weight | 186.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(2-Fluorophenyl)-1H-pyrrole-2-carbonitrile (CAS 136773-60-9) is a high-purity analytical reference standard with the molecular formula C11H7FN2 and a molecular weight of 186.19 g/mol.
The molecular framework of 1-(2-Fluorophenyl)-1H-pyrrole-2-carbonitrile (C11H7FN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 1-(2-Fluorophenyl)-1H-pyrrole-2-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H7FN2 |
| Molecular Weight | 186.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- 4-(2-Fluorophenyl)-1H-pyrrole-3-carbonitrile (CAS 103418-03-7)
- 2-(1-(4-Fluorophenyl)ethylidene)malononitrile (CAS 579-48-6)
- 4-(4-Fluorophenyl)-1H-pyrrole-3-carbonitrile (CAS 87388-08-7)
- [(4-Fluorophenyl)thio]acetic acid (CAS 332-51-4)
- 2-((3-Fluorophenyl)thio)acetic acid (CAS 331-55-5)
- 2-[(2-fluorophenyl)sulfanyl]acetic acid (CAS 705-02-2)
- 1-(2-Fluorophenyl)piperazine (CAS 1011-15-0)
- 2-(4-Fluorophenyl)-2-oxoacetyl chloride (CAS 105457-90-7)
Recommended Standards
- 8-Fluorobenzo[4,5]imidazo[1,2-a]pyridine (CAS 136343-75-4)
- 6-Fluoro-2-methylquinoline-4-carbonitrile (CAS 1368188-46-8)
- 4-(Methoxycarbonyl)thiophene-2-carboxylic acid (CAS 135080-15-8)
- 2-Fluoro-6-(1h-pyrrol-1-yl)benzonitrile (CAS 148901-51-3)
- Methyl 4-(2-fluorophenyl)thieno[3,2-c]pyridine-6-carboxylate (CAS 1344704-45-5)
- N-(furan-2-ylmethyl)-4-methoxy-7-methylbenzo[d]thiazol-2-amine (CAS 1350989-14-8)
- 2,6-Bis(benzyloxy)-3-(4-bromophenyl)pyridine (CAS 2736510-43-1)
- N-((5-Nitrofuran-2-yl)methylene)-3-phenylisoxazol-5-amine (CAS 37853-13-7)
- 6-Methyl-7-oxo-1-tosyl-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-4-boronic Acid Pinacol Ester (CAS 1445993-89-4)
- 2-Fluoropyridin-3-amine hydrochloride (CAS 1827-26-5)
- ISC-4 (CAS 1072807-15-8)
- 4-Bromo-3-[(Boc(methyl)amino)methyl]-1-methylpyrazole-5-carbonitrile (CAS 1454848-24-8)
- 6-(Cyanomethyl)-3-(difluoromethyl)-5-fluoropicolinonitrile (CAS 1807161-16-5)
- Neuropeptide W-23 (rat) (CAS 383415-89-2)
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