2-[(2-fluorophenyl)sulfanyl]acetic acid CAS 705-02-2
| CAS No. | 705-02-2 |
| Molecular Formula | C8H7FO2S |
| Molecular Weight | 186.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-[(2-fluorophenyl)sulfanyl]acetic acid (CAS 705-02-2) is a high-purity analytical reference standard with the molecular formula C8H7FO2S and a molecular weight of 186.20 g/mol.
The molecular framework of 2-[(2-fluorophenyl)sulfanyl]acetic acid (C8H7FO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 2-[(2-fluorophenyl)sulfanyl]acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7FO2S |
| Molecular Weight | 186.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related fluorophenyl Standards
- [(4-Fluorophenyl)thio]acetic acid (CAS 332-51-4)
- 2-((3-Fluorophenyl)thio)acetic acid (CAS 331-55-5)
- 4-(2-Fluorophenyl)-1H-pyrrole-3-carbonitrile (CAS 103418-03-7)
- 1-(2-Fluorophenyl)-1H-pyrrole-2-carbonitrile (CAS 136773-60-9)
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- 2-(4-Fluorophenyl)-2-oxoacetyl chloride (CAS 105457-90-7)
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- RAF 265 (CAS 927880-90-8)
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- (4-Ethylphenyl)(furan-2-yl)methanethione (CAS 1443306-30-6)
- 2,4-Dibromo-6-(trifluoromethyl)aniline (CAS 71757-14-7)
- 3-(4-Fluorophenoxy)propan-1-amine hydrochloride (CAS 148941-98-4)
- 1-(carbamoylamino)-1-oxopropan-2-yl 4-{[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]methyl}benzoate (CAS 937874-01-6)
- Semaglutide impurity 244(Fmoc-His(Fmoc)-Aib-OH) (CAS CATO-C4X-2226244)
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