[1,3]dioxolo[4,5-β]pyridine CAS 72138-73-9
| CAS No. | 72138-73-9 |
| Molecular Formula | C6H5NO2 |
| Molecular Weight | 123.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
[1,3]dioxolo[4,5-β]pyridine (CAS 72138-73-9), molecular formula C6H5NO2 and molecular weight 123.11 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, [1,3]dioxolo[4,5-β]pyridine (C6H5NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 123.11 g/mol, it falls into the low-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), [1,3]dioxolo[4,5-β]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5NO2 |
| Molecular Weight | 123.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 1 |
Related dioxolo Standards
- [1,3]Dioxolo[4,5-b]pyridin-6-amine (CAS 1367946-80-2)
- 2H-[1,3]dioxolo[4,5-b]pyridin-5-amine (CAS 1368345-12-3)
- [1,3]Dioxolo[4,5-b]pyridin-6-ol (CAS 1019767-69-1)
- [1,3]Dioxolo[4,5-d]pyrrolo[1,2-b]isoxazole (CAS 127493-26-9)
- [1,3]Dioxolo[4,5-b]pyridine-6-carbaldehyde (CAS 76470-45-6)
- 2h-[1,3]dioxolo[4,5-c]pyridine-6-carbaldehyde (CAS 959617-89-1)
- [1,3]Dioxolo[4,5-b]pyridin-7-ylmethanamine (CAS 1260667-39-7)
- [1,3]Dioxolo[4,5-b]pyridin-6-ylmethanamine (CAS 1260671-81-5)
Recommended Standards
- (Z)-5-(2-Hydroxyvinyl)-2H-pyrrol-2-one (CAS 922179-84-8)
- 1-(Hydroxymethyl)-1H-pyrazole-3-carbonitrile (CAS 860807-23-4)
- (E)-2-Pyrimidinecarboxaldehydeoxime (CAS 39232-40-1)
- 1,6-Dihydro-5H-imidazo[1,5-a]imidazol-5-one (CAS 518036-07-2)
- Ethyl 5-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl)-1,3,4-thiadiazole-2-carboxylate (CAS 1142209-48-0)
- 2-(Aminomethyl)-6-(difluoromethyl)pyridine-4-carboxylic acid (CAS 1805011-79-3)
- 2-hydroxyimidazo[1,2-a]pyridine-6-carboxylic acid hydrochloride (CAS 1803608-91-4)
- 1-(4-Chlorophenyl)-3-cyclohexyl-1H-pyrazol-5-amine (CAS 1225929-99-6)
- 1-(2-Hydroxyphenyl)-2-methoxyethanone (CAS 138206-45-8)
- 3-(4-Isopropylpiperazin-1-yl)indolizine-6-carboxylic acid (CAS 1422066-99-6)
- N-(4-Amino-1,3,5-triazin-2-yl)-4-methylbenzamide (CAS 806635-24-5)
- 3-bromo-4-chloro-1-[(4-methoxyphenyl)methyl]pyrazolo[3,4-b]pyridine (CAS 1854056-69-1)
- Glycopyrrolate Impurity 7 (CAS CATO-C4X-18177)
- D-Pro37-Tirzepatide (CAS CATO-CPTD788902)
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