5-(5-Chlorothiophen-2-yl)-1,2-oxazole-4-carboxylic acid CAS 1368489-92-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1368489-92-2
Molecular FormulaC8H4ClNO3S
Molecular Weight229.64 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(5-Chlorothiophen-2-yl)-1,2-oxazole-4-carboxylic acid CAS 1368489-92-2 chemical structure

Description

The molecular framework of 5-(5-Chlorothiophen-2-yl)-1,2-oxazole-4-carboxylic acid (C8H4ClNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

CATO supplies 5-(5-Chlorothiophen-2-yl)-1,2-oxazole-4-carboxylic acid (CAS 1368489-92-2), a certified reference material (molecular formula C8H4ClNO3S, MW 229.64 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(5-Chlorothiophen-2-yl)-1,2-oxazole-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H4ClNO3S
Molecular Weight229.64 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

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