5-(5-Chlorothiophen-2-yl)-1,2-oxazole-3-carboxylic acid CAS 933686-84-1
| CAS No. | 933686-84-1 |
| Molecular Formula | C8H4ClNO3S |
| Molecular Weight | 229.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(5-Chlorothiophen-2-yl)-1,2-oxazole-3-carboxylic acid.
5-(5-Chlorothiophen-2-yl)-1,2-oxazole-3-carboxylic acid (CAS 933686-84-1), molecular formula C8H4ClNO3S and molecular weight 229.64 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 5-(5-Chlorothiophen-2-yl)-1,2-oxazole-3-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 229.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(5-Chlorothiophen-2-yl)-1,2-oxazole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4ClNO3S |
| Molecular Weight | 229.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorothiophen Standards
- 5-(5-Chlorothiophen-2-yl)-1,2-oxazole-4-carboxylic acid (CAS 1368489-92-2)
- (5-Chlorothiophen-2-yl)(thiazol-2-yl)methanone (CAS 1379312-60-3)
- n-((5-Chlorothiophen-2-yl)methyl)-3-methylbut-2-enamide (CAS 1211305-95-1)
- (5-Chlorothiophen-2-yl)(piperidin-1-yl)methanone (CAS 950237-38-4)
- 1-(3-Chlorothiophen-2-yl)-3-(dimethylamino)but-2-en-1-one (CAS 860788-52-9)
- 1-(5-Chlorothiophen-2-yl)-3-(dimethylamino)but-2-en-1-one (CAS 860788-50-7)
- n-(1-(5-Chlorothiophen-2-yl)ethyl)cyclopentanamine (CAS 1154576-50-7)
- (1-(5-Chlorothiophen-2-yl)cyclohexyl)methanamine (CAS 924867-41-4)
Recommended Standards
- 4-Chloro-6-nitrobenzo[d]thiazol-2-amine (CAS 66188-30-5)
- Benzonitrile, 4-chloro-5-(dimethoxymethyl)-2-fluoro- (CAS 2771128-00-6)
- (5R)-5-(Chloromethyl)-3-(3-fluorophenyl)-2-oxazolidinone (CAS 879215-66-4)
- Methyl (E)-3-(6-amino-3-chloro-2-fluorophenyl)acrylate (CAS 2781127-95-3)
- 2-((2,4-Dioxo-6-(((2S,3S,4R)-2,3,4,5-tetrahydroxypentyl)amino)-1,2,3,4-tetrahydropyrimidin-5-yl)imino)acetone (CAS 1610526-18-5)
- 6H-Thiazolo[5,4-e]indol-7(8H)-one (CAS 222036-27-3)
- 1’-Acetyl-2,7-dibromospiro[fluorene-9,4’-piperidine] (CAS 1616114-00-1)
- 2,2,2-Trifluoroethyl (6-(pyrrolidin-1-yl)pyridin-3-yl)carbamate (CAS 1221723-70-1)
- N-[[(2S)-1-Ethyl-2-pyrrolidinyl]methyl]carbamic Acid 1,1-Dimethylethyl Ester (CAS 883555-07-5)
- 7-Fluoro-6-nitro-1,2,3,4-tetrahydroquinolin-2-one (CAS 1146289-84-0)
- 4-Methylbenzyl acetate (CAS 2216-45-7)
- Methyl 6-((5-cyanopyrazin-2-yl)amino)-4-((piperidin-4-ylmethyl)amino)nicotinate (CAS 1137475-91-2)
- 1,2-Di-m-tolylethane-1,2-diol (CAS 24133-60-6)
- [3-31]-Semaglutide D (CAS C152H230N42O47)
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