2-(3-Fluorophenyl)-5-methylthiazole-4-carboxylic acid CAS 1368548-10-0
| CAS No. | 1368548-10-0 |
| Molecular Formula | C11H8FNO2S |
| Molecular Weight | 237.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(3-Fluorophenyl)-5-methylthiazole-4-carboxylic acid (C11H8FNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(3-Fluorophenyl)-5-methylthiazole-4-carboxylic acid (CAS 1368548-10-0), molecular formula C11H8FNO2S and molecular weight 237.25 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(3-Fluorophenyl)-5-methylthiazole-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8FNO2S |
| Molecular Weight | 237.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- 4-(3-Fluorophenyl)-2-methylthiazole-5-carboxylic acid (CAS 1007873-59-7)
- 2-(2-Fluorophenyl)-5-methylthiazole-4-carboxylic acid (CAS 1017421-73-6)
- 2-[(2-fluorophenyl)methyl]-1,3-thiazole-5-carboxylic acid (CAS 1018297-66-9)
- 2-(3-Fluorophenyl)-4-methylthiazole-5-carboxylic acid (CAS 1027513-59-2)
- Methyl 5-(4-fluorophenyl)thiazole-4-carboxylate (CAS 1038508-99-4)
- 2-[(4-fluorophenyl)methyl]-1,3-thiazole-5-carboxylic acid (CAS 1094230-04-2)
- 2-[(4-fluorophenyl)methyl]-1,3-thiazole-4-carboxylic acid (CAS 1094291-21-0)
- 4-(2-Fluorophenyl)-2-methylthiazole-5-carboxylic acid (CAS 1188184-08-8)
Recommended Standards
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- Ethyl 2-((4-ethoxyphenyl)amino)-2-oxoacetate (CAS 13789-91-8)
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- 2-((4-Oxo-3,7-diphenyl-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-2-yl)thio)acetonitrile (CAS 1040646-99-8)
- N-Butyl-2,5-dichloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzamide (CAS 898425-58-6)
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- Semaglutide impurity 22(OtBu-Ste-γGlu(OtBu)-AEEA-AEEA-OH) (CAS 1118767-16-0)
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