Ropinirole Impurity 6 CAS 1368745-05-4
| CAS No. | 1368745-05-4 |
| Molecular Formula | C10H9NO |
| Molecular Weight | 159.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Ropinirole Impurity 6 (CAS 1368745-05-4, C10H9NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C10H9NO, Ropinirole Impurity 6 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 159.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9NO |
| Molecular Weight | 159.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Related Ropinirole Standards
- Ropinirole Impurity 4 (CAS 120427-93-2)
- Ropinirole Impurity N68 (CAS 954117-24-9)
- Ropinirole EP Impurity F (CAS 139122-19-3)
- Ropinirole Impurity 9 (CAS 23876-15-5)
- Ropinirole Impurity 20 (CAS CATO-C4X-174520)
- Ropinirole Impurity 10 (CAS 101566-00-1)
- Ropinirole EP Impurity D (CAS 106916-16-9)
- Ropinirole Impurity 17 (CAS 120427-96-5)
Recommended Standards
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- Perospirone Impurity 38 (CAS CATO-C4X-245838)
- Busulfan Impurity 7 (CAS 26910-61-2)
- Folic Acid Impurity 25 (CAS 694514-39-1)
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- Tirzepatide (CAS 2023788-19-2)
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