Busulfan Impurity 7 CAS 26910-61-2

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.26910-61-2
Molecular FormulaC5H11ClO3S
Molecular Weight186.66 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Busulfan Impurity 7 CAS 26910-61-2 chemical structure

Description

The molecular framework of Busulfan Impurity 7 (C5H11ClO3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Busulfan Impurity 7 (CAS 26910-61-2) is a certified pharmaceutical impurity reference standard with the molecular formula C5H11ClO3S and a molecular weight of 186.66 g/mol.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC5H11ClO3S
Molecular Weight186.66 g/mol
Purity>95%
StorageStore at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityHygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)0.0
CAS Registry Year (est.)1964
Halogen ContentCl-containing
Sulfur Atoms1

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