6-Chloro-1,3-dimethyl-1H-indole CAS 1368932-07-3
| CAS No. | 1368932-07-3 |
| Molecular Formula | C10H10ClN |
| Molecular Weight | 179.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-Chloro-1,3-dimethyl-1H-indole (C10H10ClN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
6-Chloro-1,3-dimethyl-1H-indole (CAS 1368932-07-3) is a high-purity analytical reference standard with the molecular formula C10H10ClN and a molecular weight of 179.65 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10ClN |
| Molecular Weight | 179.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 7-Chloro-2,3-dimethyl-1H-indole (CAS 107327-44-6)
- 5-Chloro-1-ethyl-1H-indole (CAS 112194-57-7)
- 4-Chloro-5,7-dimethylindole (CAS 1167055-63-1)
- 5-Chloro-4,7-dimethyl-1H-indole (CAS 1227268-59-8)
- 2-Chloro-5-isopropylbenzonitrile (CAS 1242339-56-5)
- 4-Chloro-3-isopropylbenzonitrile (CAS 1349716-25-1)
- 2-Chloro-3,5-dimethyl-1H-indole (CAS 1352485-23-4)
- 2-Chloro-3,7-dimethyl-1H-indole (CAS 1352530-49-4)
Recommended Standards
- 3-(Chloromethyl)-1-methyl-1H-indole (CAS 1368886-47-8)
- 6'-Chlorospiro[cyclopropane-1,3'-indoline] (CAS 1403899-01-3)
- 6-Chloro-1-methyl-3,4-dihydroisoquinoline (CAS 135365-26-3)
- 6-(Chloromethyl)-1-methyl-1H-indole (CAS 1429441-30-4)
- N-Acetyl Demethyl Memantine (CAS 778-09-6)
- (E)-4-(2-(4-hydroxybenzoyl)hydrazinyl)-4-oxobut-2-enoic acid (CAS 296265-27-5)
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- 2-Chloro-N-(4-phenyl-1,3-thiazol-2-yl)propanamide (CAS 83758-08-1)
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