Lemborexant impurity 01 CAS 1369768-29-5
| CAS No. | 1369768-29-5 |
| Molecular Formula | C13H15FO3 |
| Molecular Weight | 238.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Lemborexant impurity 01 (CAS 1369768-29-5) is a certified pharmaceutical impurity reference standard with the molecular formula C13H15FO3 and a molecular weight of 238.25 g/mol.
The molecular framework of Lemborexant impurity 01 (C13H15FO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lemborexant impurity 01 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H15FO3 |
| Molecular Weight | 238.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Lemborexant Standards
- Lemborexant impurity 13 (CAS CATO-C4X-304213)
- Lemborexant Impurity 57 (CAS CATO-C4X-304257)
- Lemborexant Impurity 86 (CAS CATO-C4X-304286)
- Lemborexant Impurity 87 (CAS CATO-C4X-304287)
- Lemborexant Impurity 94 (CAS CATO-C4X-304294)
- Lemborexant Impurity 63 (CAS 1872428-94-8)
- Lemborexant Impurity 98 (CAS CATO-C4X-304298)
- Lemborexant Impurity 55 (CAS CATO-C4X-304255)
Recommended Standards
- 4-(2-Fluorobenzyl)tetrahydro-2H-pyran-4-carboxylic acid (CAS 1272802-31-9)
- 4-(4-Fluorobenzyl)tetrahydro-2h-pyran-4-carboxylic acid (CAS 1380300-55-9)
- 1-(4-Fluorophenoxy)cyclohexanecarboxylic acid (CAS 1267028-24-9)
- 4-(3-Fluorobenzyl)tetrahydro-2h-pyran-4-carboxylic acid (CAS 1380300-75-3)
- Betamethasone Impurity 30 (CAS 52619-21-3)
- Tolterodine impurity 33 (CAS CATO-C4X-176733)
- Tamsulosin Impurity 14 (CAS CATO-C4X-118714)
- Methyl 5-chloro-3-methylpicolinate (CAS 886365-49-7)
- 4-Butoxy-3,5-dichloro-benzaldehyde (CAS 50906-43-9)
- Potassium oleate (CAS 143-18-0)
- 2-Chloro-5-(4-fluorophenyl)pyrazine (CAS 115104-61-5)
- 2-Bromo-4-chloro-6-(difluoromethyl)-3-(trifluoromethyl)pyridine (CAS 1806933-57-2)
- (2R,4R)-8,9-diazatricyclo[4.3.0.0²⁴]nona-1(6),7-diene-7-carboxylic acid (CAS 1268882-43-4)
- Semaglutide Impurity 185 (CAS CATO-C4X-2226185)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com