Lemborexant Impurity 57 CAS CATO-C4X-304257
| CAS No. | CATO-C4X-304257 |
| Molecular Formula | C13H15FO3 |
| Molecular Weight | 238.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lemborexant Impurity 57.
CATO supplies Lemborexant Impurity 57 (CAS CATO-C4X-304257), a pharmacopoeial impurity reference standard (molecular formula C13H15FO3, MW 238.25 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C13H15FO3, Lemborexant Impurity 57 contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 238.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H15FO3 |
| Molecular Weight | 238.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Lemborexant Standards
- Lemborexant impurity 01 (CAS 1369768-29-5)
- Lemborexant impurity 13 (CAS CATO-C4X-304213)
- Lemborexant Impurity 86 (CAS CATO-C4X-304286)
- Lemborexant Impurity 87 (CAS CATO-C4X-304287)
- Lemborexant Impurity 94 (CAS CATO-C4X-304294)
- Lemborexant Impurity 63 (CAS 1872428-94-8)
- Lemborexant Impurity 98 (CAS CATO-C4X-304298)
- Lemborexant Impurity 55 (CAS CATO-C4X-304255)
Recommended Standards
- Minoxidil impurity 48 (CAS 1350513-60-8)
- Topiroxostat Impurity 25 (CAS 31599-25-4)
- Topiroxostat Impurity 19 (CAS 38634-05-8)
- 2-Cyano-N-(4-(methylsulfonyl)phenyl)acetamide (CAS 1016833-99-0)
- Flurbiprofen Impurity 27 (CAS CATO-C4X-144427)
- Sotorasib impurity 1 (CAS CATO-C4X-31031)
- Axitinib Impurity 32 (CAS CATO-C4X-107132)
- Orbifloxacin impurity 12 (CAS CATO-C4X-256712)
- [4-(Isopentyloxy)phenyl]-N-(tetrahydro-2-furanylmethyl)methanamine (CAS 1036567-89-1)
- ethyl 3-acetyl-4-oxocyclohexane-1-carboxylate (CAS 107861-64-3)
- Trielaidin (CAS 537-39-3)
- 2-(2-Methylpropoxy)-1-nitro-4-(trifluoromethyl)benzene (CAS 1881329-89-0)
- Hydrochlorothiazide EP Impurity B (CAS 121-30-2)
- Insulin Degludec Impurity 8 (CAS CATO-C4X-21578)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com