N-(5-Chloro-2-methoxyphenyl)-3-hydroxy-2-naphthamide CAS 137-52-0
| CAS No. | 137-52-0 |
| Molecular Formula | C18H14ClNO3 |
| Molecular Weight | 327.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, N-(5-Chloro-2-methoxyphenyl)-3-hydroxy-2-naphthamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 327.76 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies N-(5-Chloro-2-methoxyphenyl)-3-hydroxy-2-naphthamide (CAS 137-52-0), a certified reference material (molecular formula C18H14ClNO3, MW 327.76 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H14ClNO3 |
| Molecular Weight | 327.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 5-(Benzyloxy)-2-(5-chloropyridin-3-yl)-4-methoxypyrimidine (CAS 1632286-26-0)
- N-(2-((2-chlorophenyl)amino)-2-oxoethyl)-1H-indole-3-carboxamide (CAS 1323558-96-8)
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- 3-(2-Chloroethyl)-4-oxo-3,4-dihydropyrazolo[5,1-d][1,2,3,5]tetrazine-8-carboxamide (CAS 90521-23-6)
- 4-(2-Piperidin-2-yl-ethyl)-morpholine (CAS 216985-68-1)
- Ticagrelor Impurity 74 (CAS 220352-36-3)
- 3-Chloro-5-methylisonicotinic acid (CAS 1256835-78-5)
- (R)-2-Amino-3-hydroxypropanamide (CAS 104714-52-5)
- 2-(4-Nitrophenoxy)propanoic acid (CAS 13794-10-0)
- 2-Chloro-2-(2,6-dichlorophenyl)acetonitrile (CAS 1247531-20-9)
- 1,3-Difluoro-2-iodo-4-(trifluoromethyl)benzene (CAS 2089257-26-9)
- Myelin Basic Protein (85-99) Peptide Antagonist (CAS 444305-16-2)
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