Ticagrelor Impurity 74 CAS 220352-36-3
| CAS No. | 220352-36-3 |
| Molecular Formula | C10H8F2O2 |
| Molecular Weight | 198.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ticagrelor Impurity 74 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Ticagrelor Impurity 74 (CAS 220352-36-3) is a certified pharmaceutical impurity reference standard with the molecular formula C10H8F2O2 and a molecular weight of 198.17 g/mol.
Based on its molecular formula C10H8F2O2, Ticagrelor Impurity 74 contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 198.17 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C10H8F2O2 |
| Molecular Weight | 198.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | F-containing |
Related Ticagrelor Standards
- Ticagrelor impurity 136 (CAS 1932275-13-2)
- Ticagrelor Impurity 152 (CAS 1006376-62-0)
- Ticagrelor impurity 84（trans） (CAS 1006614-51-2)
- Ticagrelor Impurity 135 (CAS CATO-C4X-1093135)
- Ticagrelor Impurity 153 (CAS CATO-C4X-1093153)
- Ticagrelor Impurity 173 (CAS 1212376-05-0)
- Ticagrelor Impurity N40 (CAS 1006376-60-8)
- Ticagrelor Impurity 78 (CAS 1351990-36-7)
Recommended Standards
- 3-hydroxy-4,5-dimethoxybenzoic acid (CAS 1916-08-1)
- Acotiamide Impurity 11 (CAS 5722-93-0)
- 3330AF 6-(Difluoromethyl)-4-methyl-1H-pyrazolo[3,4-b]-pyridin-3-amine 925146-05-0 C8H8F2N4 (CAS 925146-05-0)
- Salbutamol Glyoxal Impurity (CAS CATO-C4X-1176167)
- Dolutegravir Impurity 5 (CAS 2244161-71-3)
- Tezacaftor Impurity 1 (CAS 2229860-93-7)
- Arbidol Impurity 20 (CAS CATO-C4X-112920)
- 2,5-Dibromo-3-methoxybenzaldehyde (CAS 856767-02-7)
- 3-[3-(trifluoromethyl)benzoyl]pyridine (CAS 59190-60-2)
- Ethyl 2-oxobutanoate (CAS 15933-07-0)
- 4-Bromobenzimidamide hydrochloride (CAS 55368-42-8)
- 4-Bromo-2,6-diisopropyl-N,N-dimethylaniline (CAS 930781-28-5)
- 1-(Spiro[2.2]pentan-1-yl)ethan-1-ol (CAS 1822863-22-8)
- Anti-Inflammatory Peptide 3 (CAS 118850-73-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com