Dabigatran Impurity 147 CAS 1370605-46-1
| CAS No. | 1370605-46-1 |
| Molecular Formula | C10H14N2O3 |
| Molecular Weight | 210.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Dabigatran Impurity 147 (CAS 1370605-46-1), a pharmacopoeial impurity reference standard (molecular formula C10H14N2O3, MW 210.23 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Dabigatran Impurity 147 (C10H14N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14N2O3 |
| Molecular Weight | 210.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Dabigatran Standards
- Dabigatran Etexilate Impurity 2 (CAS 333350-60-0)
- Dabigatran Impurity 87 (CAS 36242-50-9)
- Dabigatran Impurity 103 (CAS CATO-C4X-1089103)
- Dabigatran Impurity 83 (CAS 218168-58-2)
- Dabigatran Impurity 114 (CAS CATO-C4X-1089114)
- Dabigatran Impurity 69 (CAS 41263-74-5)
- Dabigatran Impurity 78 (CAS 1369943-91-8)
- Dabigatran Impurity 68 (CAS 103041-38-9)
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- Milnacipran impurity 01 (CAS 69160-65-2)
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- Arotinolol Impurity 3 (CAS CATO-C4X-18543)
- Ethyl 2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate (CAS 261767-10-6)
- N,1-Dimethylpyrrolidine-2-carboxamide (CAS 99767-11-0)
- N-Isopentyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine (CAS 2096332-90-8)
- Eledoisin Related Peptide (CAS 2990-43-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com