Citalopram Impurity 48 Chloride CAS 1370643-27-8
| CAS No. | 1370643-27-8 |
| Molecular Formula | C40H41F2N4O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Citalopram Impurity 48 Chloride (CAS 1370643-27-8) is a certified pharmaceutical impurity reference standard with the molecular formula C40H41F2N4OCl and a molecular weight of 667.24 g/mol.
Citalopram Impurity 48 Chloride (C40H41F2N4OCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Citalopram Impurity 48 Chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C40H41F2N4O Cl |
| Molecular Weight | 667.24 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Citalopram Standards
- Citalopram Impurity 38 (CAS 103146-26-5)
- Citalopram Impurity 17 (CAS 1187671-15-3)
- Citalopram EP Impurity D HBr (CAS 1188264-72-3)
- Citalopram-d6 N-Oxide (CAS 1189652-54-7)
- Citalopram-d6 (CAS 1190003-26-9)
- (R)-Citalopram-d6 N-Oxide (CAS 1217669-62-9)
- (S)-Citalopram-d6 N-Oxide (CAS 1217710-65-0)
- (S)-Citalopram-d6 Oxalate (CAS 1217733-09-9)
Recommended Standards
- Dapagliflozin Impurity 140 (CAS 912917-85-2)
- Dalilesen Impurity 61 (CAS CATO-C4X-301061)
- Vonoprazan Impurity 138 (CAS CATO-C4X-1020138)
- 6-Oxo-1,6-dihydropyridine-3-carbonitrile (CAS 95891-30-8)
- 3-Phenyl-2-(piperazin-1-ylmethyl)-3H-imidazo[4,5-b]pyridine (CAS 1172973-22-6)
- 3-Aminoisonicotinaldehyde dihydrochloride (CAS 1220039-62-2)
- 6-(4-Chlorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazole (CAS 4335-32-4)
- tert-Butyl 3-(2,6-difluorophenyl)-3-hydroxyazetidine-1-carboxylate (CAS 1489907-45-0)
- 4-Fluoro-3aH-indazol-3-amine (CAS 697230-91-4)
- Gastric Inhibitory Polypeptide (human) (CAS 100040-31-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com