Quetiapine EP Impurity K CAS 1371638-10-6
| CAS No. | 1371638-10-6 |
| Molecular Formula | C23H29N3O4S |
| Molecular Weight | 443.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Quetiapine EP Impurity K (C23H29N3O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 443.56 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Quetiapine EP Impurity K (CAS 1371638-10-6), a pharmacopoeial impurity reference standard (molecular formula C23H29N3O4S, MW 443.56 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H29N3O4S |
| Molecular Weight | 443.56 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Quetiapine Standards
- Quetiapine Impurity 3 (CAS CATO-C4X-12443)
- Quetiapine Impurity N3 (CAS 102893-57-2)
- Quetiapine Carboxylate Impurity (CAS 1011758-00-1)
- Quetiapine EP Impurity A (CAS 844639-07-2)
- Quetiapine EP Impurity L (CAS 1371638-11-7)
- Quetiapine impurity 73 (CAS CATO-C4X-124473)
- Quetiapine Impurity 35 (CAS 329216-65-1)
- Quetiapine Impurity 51 (CAS 1185170-04-0)
Recommended Standards
- N-(4-(N-(1-Isopentyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)sulfamoyl)phenyl)propionamide (CAS 942003-50-1)
- Neostigmine impurity 46 (CAS CATO-C4X-204246)
- N-(4-(N-(1-Isobutyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)sulfamoyl)phenyl)butyramide (CAS 942003-23-8)
- (S)-(-)-Valsartan-d8 (valine-d8) (CAS 1089736-72-0)
- Levocabastine EP impurity E (CAS 105452-51-5)
- Anagrelide Impurity 22 (CAS 20098-48-0)
- Saxagliptin Impurity 6 (CAS 1334321-39-9)
- 1-(Benzo[d]thiazol-2-yl)-3-(4-methoxyphenyl)-1H-pyrazol-5-ol (CAS 431074-72-5)
- diethyl 2-[(4-chloroanilino)methylene]malonate (CAS 19056-79-2)
- 1-Methoxyisoquinoline-4-carbonitrile (CAS 87954-16-3)
- Suc-Leu-Tyr-AMC (CAS 94367-20-1)
- 4-(2-Bromophenoxy)tetrahydro-2H-pyran (CAS 494773-65-8)
- nonane-1-sulfonyl chloride (CAS 63353-34-4)
- (Gly1,Ser3·22,Gln?·3?,Thr?,Arg1?,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) (CAS 313988-89-5)
Why CATO?
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