Methyl 5-bromo-2-(1,1-dioxidoisothiazolidin-2-yl)benzoate CAS 1373232-33-7
| CAS No. | 1373232-33-7 |
| Molecular Formula | C11H12BrNO4S |
| Molecular Weight | 334.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 5-bromo-2-(1,1-dioxidoisothiazolidin-2-yl)benzoate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methyl 5-bromo-2-(1,1-dioxidoisothiazolidin-2-yl)benzoate (CAS 1373232-33-7) is a high-purity analytical reference standard with the molecular formula C11H12BrNO4S and a molecular weight of 334.19 g/mol.
The molecular framework of Methyl 5-bromo-2-(1,1-dioxidoisothiazolidin-2-yl)benzoate (C11H12BrNO4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 5-bromo-2-(1,1-dioxidoisothiazolidin-2-yl)benzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12BrNO4S |
| Molecular Weight | 334.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- DIethyl 2-{[(6-methoxypyridin-3-yl)amino]methylene}malonate (CAS 53241-90-0)
- D-[γ-Glu](Side Chain)-Semaglutide (CAS CATO-C4X-2226254)
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