2-Bromo-5-(pyrrolidine-1-sulfonyl)benzoic acid CAS 22361-65-5
| CAS No. | 22361-65-5 |
| Molecular Formula | C11H12BrNO4S |
| Molecular Weight | 334.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-5-(pyrrolidine-1-sulfonyl)benzoic acid.
2-Bromo-5-(pyrrolidine-1-sulfonyl)benzoic acid (CAS 22361-65-5), molecular formula C11H12BrNO4S and molecular weight 334.19 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Bromo-5-(pyrrolidine-1-sulfonyl)benzoic acid (C11H12BrNO4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 334.19 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Bromo-5-(pyrrolidine-1-sulfonyl)benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12BrNO4S |
| Molecular Weight | 334.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromo Standards
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Recommended Standards
- 2-[2-(Dimethylamino)ethoxy]-5-fluoro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile (CAS 2377610-85-8)
- 2,5-Dichloro-N-(4-fluorobenzyl)benzenesulfonamide (CAS 560077-03-4)
- 2-(5-Bromothiophen-2-yl)quinoline-4-carboxylic acid (CAS 351982-36-0)
- N-(6-Bromothiazolo[4,5-b]pyridin-2-yl)benzamide (CAS 588729-97-9)
- ((Allyloxy)carbonyl)-L-phenylalanine (CAS 90508-20-6)
- 2-Amino-6-(difluoromethyl)-4-nitronicotinic acid (CAS 1804719-82-1)
- 3,3-Difluoro-4-piperidinecarboxylic acid (CAS 1303974-04-0)
- 1-(5-Fluoropyridin-2-yl)ethan-1-amine dihydrochloride (CAS 1955519-79-5)
- 2'-Amino-1-[(2-chlorophenyl)methyl]-7'-methyl-2,5'-dioxo-1,2-dihydro-5'H-spiro[indole-3,4'-pyrano[3,2-c]pyran]-3'-carbonitrile (CAS 900265-65-8)
- 3-(3,5-Dimethyl-1H-pyrazol-1-yl)cyclohexan-1-one (CAS 1513184-34-3)
- 2-Fluoro-5-methyl-3-(trifluoromethoxy)aniline (CAS 1803822-45-8)
- N-[5-(Aminomethyl)pyridin-2-yl]propanamide (CAS 1250210-66-2)
- 2-Cyclopropyl-1,3-oxazole-4-carbonyl chloride (CAS 1072103-26-4)
- RGD-targeted Proapoptotic Peptide trifluoroacetate salt (CAS 2243207-09-0)
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