<I>N,N</I>-Diisopropylphosphoramidite di<I>tert</I>butyl CAS 137348-86-8

Purity 97%+In StockPharmaceutical Standards
CAS No.137348-86-8
Molecular FormulaC14H32NO2P
Molecular Weight277.38 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

<I>N,N</I>-Diisopropylphosphoramidite di<I>tert</I>butyl CAS 137348-86-8 chemical structure

Description

The molecular framework of <I>N,N</I>-Diisopropylphosphoramidite di<I>tert</I>butyl (C14H32NO2P) is characterized by an amide group, organophosphorus functionality, a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

<I>N,N</I>-Diisopropylphosphoramidite di<I>tert</I>butyl (CAS 137348-86-8) is a high-purity analytical reference standard with the molecular formula C14H32NO2P and a molecular weight of 277.38 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures <I>N,N</I>-Diisopropylphosphoramidite di<I>tert</I>butyl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC14H32NO2P
Molecular Weight277.38 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)-0.5
CAS Registry Year (est.)1996
Nitrogen Atoms1

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