Indometacin EP Impurity E CAS 807614-94-4
| CAS No. | 807614-94-4 |
| Molecular Formula | C19H16ClNO4 |
| Molecular Weight | 357.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Indometacin EP Impurity E (CAS 807614-94-4), a pharmacopoeial impurity reference standard (molecular formula C19H16ClNO4, MW 357.79 g/mol) used for the identification and quantification of trace impurities in APIs.
Indometacin EP Impurity E (C19H16ClNO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Indometacin EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H16ClNO4 |
| Molecular Weight | 357.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Indometacin Standards
- Indometacin EP Impurity D (CAS CATO-C4X-147012)
- Indometacin Impurity 47 (CAS CATO-C4X-147047)
- Indometacin Impurity 54 (CAS CATO-C4X-147054)
- Indometacin Impurity 65 (CAS CATO-C4X-147065)
- Indometacin EP Impurity H (CAS 1601-18-9)
- Indometacin EP Impurity I (CAS 16401-99-3)
- Indometacin Impurity 55 (CAS CATO-C4X-147055)
- Indometacin EP Impurity G (CAS 402849-26-7)
Recommended Standards
- CAS 2241757-94-6 (CAS 2241757-94-6)
- N-(4-Chloro-2,5-dimethoxyphenyl)-3-hydroxy-2-naphthamide (CAS 4273-92-1)
- Methyl 1-(2-(4-chloro-3-methylphenoxy)acetyl)-1H-indole-3-carboxylate (CAS 429627-08-7)
- Lornoxicam impurity 59 (CAS CATO-C4X-201659)
- Cefcapene Impurity 51 (CAS CATO-C4X-182451)
- Mirogabalin Impurity 63 (CAS 1644251-70-6)
- Baricitinib Impurity 69 (CAS CATO-C4X-226069)
- 4-[(1E)-{[3-(trifluoromethyl)phenyl]imino}methyl]phenyl 4-chlorobenzene-1-sulfonate (CAS 298215-42-6)
- 2-(Boc-amino)-2-(3,4-dichlorophenyl)acetic Acid (CAS 142121-95-7)
- (R)-1-Methylpiperidin-3-ol (CAS 28808-26-6)
- Cytarabine Impurity 22 (CAS CATO-C4X-200522)
- 5,7-Dimethyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one (CAS 116636-30-7)
- 2-[3,4-Dihydro-2(1H)-isoquinolinyl]nicotinic acid (CAS 250739-09-4)
- Semaglutide Impurity 157 (x TFA Salt) (CAS CATO-C4X-2226157)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com