2-(3,3-Difluorocyclobutyl)acetic Acid CAS 1373503-48-0
| CAS No. | 1373503-48-0 |
| Molecular Formula | C6H8F2O2 |
| Molecular Weight | 150.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 150.12 g/mol gives 2-(3,3-Difluorocyclobutyl)acetic Acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-(3,3-Difluorocyclobutyl)acetic Acid (CAS 1373503-48-0), a certified reference material (molecular formula C6H8F2O2, MW 150.12 g/mol) for analytical method development and quality control.
The molecular framework of 2-(3,3-Difluorocyclobutyl)acetic Acid (C6H8F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(3,3-Difluorocyclobutyl)acetic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H8F2O2 |
| Molecular Weight | 150.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Difluorocyclobutyl Standards
- 3-(3,3-Difluorocyclobutyl)propan-1-ol (CAS 2228985-15-5)
- 3-(3,3-Difluorocyclobutyl)propanal (CAS 2229610-78-8)
- 2-(3,3-Difluorocyclobutyl)azetidine (CAS 2228949-43-5)
- 3-(3,3-Difluorocyclobutyl)azetidine (CAS 2228894-50-4)
- 3-(3,3-difluorocyclobutyl)propanenitrile (CAS 1798322-81-2)
- 2-(3,3-Difluorocyclobutyl)-1H-imidazole (CAS 2227205-16-3)
- 3-(3,3-difluorocyclobutyl)-3-oxopropanenitrile (CAS 1234616-26-2)
- 3-(3,3-difluorocyclobutyl)prop-2-ynoic acid (CAS 2613384-93-1)
Recommended Standards
- (R)-3,3-Difluorocyclopentanecarboxylic Acid (CAS 1352621-96-5)
- 2,2-Difluorocyclopentane-1-carboxylic acid (CAS 1378525-26-8)
- 2,2-Difluoro-3,3-dimethylcyclopropane-1-carboxylic acid (CAS 131262-35-6)
- (S)-3,3-Difluorocyclopentanecarboxylic acid (CAS 1408057-45-3)
- 2-(4-Amino-2-bromo-5-fluorophenyl)acetic acid (CAS 1260679-48-8)
- Alkannin Impurity 3 (CAS 52387-14-1)
- 1,1-Difluoro-2-methylpropan-2-amine (CAS 1513291-91-2)
- 5-Bromo-6-methyl-2-(methylthio)pyrimidin-4(3H)-one (CAS 33238-63-0)
- trans-tert-butyl (3R,4R)-3,4-diaminopyrrolidine-1-carboxylate (CAS 2173182-42-6)
- 4-Chloro-6-(pyrrolidin-1-yl)pyrimidine (CAS 939986-64-8)
- 2-(3-Isopropyl-1H-pyrazol-1-yl)-7-methoxy-8-methylquinolin-4-ol (CAS 922520-04-5)
- imidazo[2,1-b][1,3]thiazole-3-carboxylic acid (CAS 479028-73-4)
- 1-(3-Chloro-4-fluorophenyl)-3-phenylpropan-1-one (CAS 898764-42-6)
- Met(O)14-Exenatide trifluoroacetate salt (CAS 1678417-38-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com