2,2-Difluoro-3,3-dimethylcyclopropane-1-carboxylic acid CAS 131262-35-6
| CAS No. | 131262-35-6 |
| Molecular Formula | C6H8F2O2 |
| Molecular Weight | 150.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 2,2-Difluoro-3,3-dimethylcyclopropane-1-carboxylic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 150.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2,2-Difluoro-3,3-dimethylcyclopropane-1-carboxylic acid (CAS 131262-35-6), a certified reference material (molecular formula C6H8F2O2, MW 150.12 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H8F2O2 |
| Molecular Weight | 150.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
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Recommended Standards
- 3,3-Difluorocyclopentaecarboxylic acid (CAS 1260897-05-9)
- (R)-3,3-Difluorocyclopentanecarboxylic Acid (CAS 1352621-96-5)
- Methyl 3,3-difluorocyclobutanecarboxylate (CAS 1234616-13-7)
- 2-(3,3-Difluorocyclobutyl)acetic Acid (CAS 1373503-48-0)
- 2,3,4,5-Tetramethylthiophene (CAS 14503-51-6)
- 2-(2-Methoxyethyl)-5,6,7,8-tetrahydropyrido[4,3-c]pyridazin-3(2h)-one (CAS 1282786-48-4)
- 2-(3-Acetyl-5-(4-fluorophenyl)-2-methyl-1H-pyrrol-1-yl)acetic acid (CAS 913837-59-9)
- 6-Oxo-1-(propan-2-yl)-1,4,5,6-tetrahydropyridazine-3-carboxylic acid (CAS 1251156-75-8)
- 4-Amino-2-(difluoromethyl)-5-hydroxynicotinoyl chloride (CAS 1805961-01-6)
- 2-(3-Bromo-5-fluoro-4-nitrophenyl)acetic acid (CAS 1804407-08-6)
- 2-{[(3,5-dimethoxyphenyl)methyl]amino}ethan-1-ol (CAS 802837-84-9)
- 3-(2,5-Difluorophenyl)-2-methylquinazolin-4(3H)-one (CAS 256955-23-4)
- 3-(6-methylheptan-2-yl)-2-sulfanyl-3,4-dihydroquinazolin-4-one (CAS 855715-17-2)
- Tirzepatide Impurity 43 (CAS CATO-C4X-324043)
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