1-[4-(2,2-difluoroethoxy)-3-methoxyphenyl]ethanamine,HCl CAS 1373866-16-0
| CAS No. | 1373866-16-0 |
| Molecular Formula | C11H15F2NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-[4-(2,2-difluoroethoxy)-3-methoxyphenyl]ethanamine,HCl.
CATO supplies 1-[4-(2,2-difluoroethoxy)-3-methoxyphenyl]ethanamine,HCl (CAS 1373866-16-0), a certified reference material (molecular formula C11H15F2NO2HCl, MW 267.70 g/mol) for analytical method development and quality control.
1-[4-(2,2-difluoroethoxy)-3-methoxyphenyl]ethanamine,HCl (C11H15F2NO2HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-[4-(2,2-difluoroethoxy)-3-methoxyphenyl]ethanamine,HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H15F2NO2 HCl |
| Molecular Weight | 267.70 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related difluoroethoxy Standards
- 2-(2,2-Difluoroethoxy)-5-nitropyridine (CAS 1018052-90-8)
- 2-(2,2-difluoroethoxy)-4-methylaniline (CAS 1018053-48-9)
- 1-(2,2-Difluoroethoxy)-2-fluoro-4-nitrobenzene (CAS 1018164-78-7)
- 6-(2,2-Difluoroethoxy)pyridin-3-amine (CAS 1050909-43-7)
- 6-(2,2-Difluoroethoxy)pyridine-3-carboxylic acid (CAS 1072855-41-4)
- 2-(2,2-Difluoroethoxy)benzonitrile (CAS 1160246-19-4)
- 1-(2,2-Difluoroethoxy)-2-iodobenzene (CAS 1160495-81-7)
- 5-(2,2-Difluoroethoxy)pyrazine-2-carboxylic acid (CAS 1174323-38-6)
Recommended Standards
- (2S,2'S,3S,3'S)-3,3'-di-tertbutyl-4,4'-bis((S)-2-methyl1-phenylpropoxy)-2,2',3,3'tetrahydro-2,2'-bibenzo[d][1,3]oxaphosphole (CAS 2169292-11-7)
- 3-Methylbenzene-1-carboximidamide hydrochloride (CAS 20680-59-5)
- Benzyl (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoate (CAS 250149-33-8)
- 2-(2-Benzothiazolyl)-3,5-diphenyltetrazolium Bromide (CAS 55699-64-4)
- 2-Amino-4-(4-chloro-1h-pyrazol-1-yl)-2-methylbutanamide (CAS 1247416-10-9)
- 3,4,5,6-Tetrahydrophthalimide (CAS 4720-86-9)
- 2,2-Difluoro-2-(4-fluorophenoxy)-N-(prop-2-en-1-yl)acetamide (CAS 338792-56-6)
- N-(Thiazol-2-yl)quinoxaline-6-carboxamide (CAS 571910-89-9)
- 2-Chloro-5-(pyrimidin-5-yl)benzoic acid (CAS 1248373-28-5)
- Semaglutide impurity 41 (CAS CATO-C4X-222641)
Why CATO?
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