4-((3-(Trifluoromethyl)phenyl)sulfonyl)benzonitrile CAS 1374864-78-4
| CAS No. | 1374864-78-4 |
| Molecular Formula | C14H8F3NO2S |
| Molecular Weight | 311.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-((3-(Trifluoromethyl)phenyl)sulfonyl)benzonitrile (CAS 1374864-78-4) is a high-purity analytical reference standard with the molecular formula C14H8F3NO2S and a molecular weight of 311.28 g/mol.
The molecular framework of 4-((3-(Trifluoromethyl)phenyl)sulfonyl)benzonitrile (C14H8F3NO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-((3-(Trifluoromethyl)phenyl)sulfonyl)benzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H8F3NO2S |
| Molecular Weight | 311.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- 5-(5-(Trifluoromethyl)benzo[b]thiophen-2-yl)-1H-pyrrole-2-carboxylic acid (CAS 1892389-82-0)
- 3-Methyl-4-{[3-(trifluoromethyl)phenyl]sulfanyl}-[1,2]oxazolo[5,4-d]pyrimidine (CAS 478045-23-7)
- 4-((3-(Trifluoromethyl)phenyl)sulfonamido)butanoic acid (CAS 85844-93-5)
- 7-Methyl-2-(4-(trifluoromethyl)phenyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one (CAS 866135-97-9)
- Ethyl 2-{[5-(trifluoromethyl)pyridin-2-yl]sulfonyl}propanoate (CAS 338962-51-9)
- (2-(Trifluoromethyl)quinazolin-4-yl)proline (CAS 1008592-58-2)
- 4-[2-(Trifluoromethyl)phenyl]-3h,4h,5h,6h,7h-imidazo[4,5-c]pyridine-6-carboxylic acid (CAS 1044177-04-9)
- 4-[4-(Trifluoromethyl)phenyl]-3h,4h,5h,6h,7h-imidazo[4,5-c]pyridine-6-carboxylic acid (CAS 1137469-04-5)
Recommended Standards
- 2-((tert-Butoxycarbonyl)amino)-5-(trifluoromethyl)thiophene-3-carboxylic acid (CAS 1260667-04-6)
- 3-(1H-Pyrrol-1-yl)-5-(trifluoromethyl)-1-benzothiophene-2-carboxylic acid (CAS 1227955-00-1)
- N-Trifluoroacetyl (2-tosyloxy)ethylamine (CAS 1951441-83-0)
- 2,6-Bis(4-fluorophenyl)nicotinic acid (CAS 1214354-54-7)
- n-((5-((Methylthio)methyl)furan-2-yl)methyl)-2-morpholinoethan-1-amine (CAS 1157967-43-5)
- 4-(2-Methylpropyl)benzoyl chloride (CAS 55340-18-6)
- 2,5-Difluoro-4-nitroaniline (CAS 1542-36-5)
- (3beta)-Cholest-5-en-3-ol-25,26,27-13C3 335080-97-2 (CAS 335080-97-2)
- 4-(4-(Benzyloxy)phenyl)-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860786-71-6)
- 1-(tert-Butyl) 3-methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-1,3-dicarboxylate (CAS 2258638-53-6)
- 2-Phenylbenzo[d]oxazol-6-amine (CAS 53421-88-8)
- Ethyl 2-((1S,3R)-3-((tert-butoxycarbonyl)amino)-1-hydroxy-4-methylpentyl)thiazole-4-carboxylate (CAS 1427513-81-2)
- Methyl 1-amino-3-methyl-1H-pyrazole-5-carboxylate (CAS 150017-57-5)
- Semaglutide impurity 60 (CAS CATO-C4X-222660)
Why CATO?
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