7-Methyl-2-(4-(trifluoromethyl)phenyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one CAS 866135-97-9
| CAS No. | 866135-97-9 |
| Molecular Formula | C13H8F3N3OS |
| Molecular Weight | 311.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Methyl-2-(4-(trifluoromethyl)phenyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one.
7-Methyl-2-(4-(trifluoromethyl)phenyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one (CAS 866135-97-9) is a high-purity analytical reference standard with the molecular formula C13H8F3N3OS and a molecular weight of 311.28 g/mol.
7-Methyl-2-(4-(trifluoromethyl)phenyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one (C13H8F3N3OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-Methyl-2-(4-(trifluoromethyl)phenyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H8F3N3OS |
| Molecular Weight | 311.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methyl Standards
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- (R)-2-(((R)-tert-butylsulfinyl)amino)-2-(2-fluoro-5-nitrophenyl)-N-(4-methoxybenzyl)-N-methylpropane-1-sulfonamide (CAS 1286777-81-8)
- Ethyl (3R,8aR)-5-(4-nitrophenyl)-3-phenyl-2,3,8,8a-tetrahydro-7H-oxazolo[3,2-a]pyridine-6-carboxylate (CAS 1893415-77-4)
- N-(Bis(dimethylamino)methylene)-N-methylmethanaminium chloride (CAS 30388-20-6)
- 1-(3,3-Dimethylbutyl)-1h-imidazol-2-amine (CAS 1343358-98-4)
- D-Tyr1-Tirzepatide (CAS CATO-CPTD788928)
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