6-Amino-5-nitropyrimidine-4(1H)-thione CAS 13754-21-7

Purity 97%+In StockPharmaceutical Standards
CAS No.13754-21-7
Molecular FormulaC4H4N4O2S
Molecular Weight172.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Amino-5-nitropyrimidine-4(1H)-thione CAS 13754-21-7 chemical structure

Description

The occurrence of 6-Amino-5-nitropyrimidine-4(1H)-thione is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

6-Amino-5-nitropyrimidine-4(1H)-thione (CAS 13754-21-7), molecular formula C4H4N4O2S and molecular weight 172.17 g/mol, is a CATO reference standard with documented purity and traceability.

6-Amino-5-nitropyrimidine-4(1H)-thione (C4H4N4O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-Amino-5-nitropyrimidine-4(1H)-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC4H4N4O2S
Molecular Weight172.17 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1960
Nitrogen Atoms4
Sulfur Atoms1

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