Atogepant impurity CAS 1375541-21-1
| CAS No. | 1375541-21-1 |
| Molecular Formula | C15H11N3O3 |
| Molecular Weight | 281.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Atogepant impurity is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 281.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Atogepant impurity (CAS 1375541-21-1, C15H11N3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Atogepant impurity meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H11N3O3 |
| Molecular Weight | 281.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
Related Atogepant Standards
- Atogepant Impurity 92 (CAS CATO-C4X-328592)
- Atogepant Impurity 32 (CAS 1375471-02-5)
- Atogepant Impurity 23 (CAS 1375541-24-4)
- Atogepant Impurity 79 (CAS CATO-C4X-328579)
- Atogepant Impurity 93 (CAS CATO-C4X-328593)
- Atogepant Impurity 37 (CAS CATO-C4X-328537)
- Atogepant Impurity 6 (CAS 1426935-94-5)
- Atogepant Impurity 7 (CAS 1375541-78-8)
Recommended Standards
- Nitrazepam EP Impurity A (CAS 36020-93-6)
- Ubrogepant Impurity 11 (CAS 2568065-21-2)
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- 1-Methyl Adenosine (CAS 15763-06-1)
- Diprophylline Impurity 2 (CAS CATO-C4X-26492)
- Pazopanib Impurity 57 (CAS CATO-C4X-172557)
- Ubrogepant Impurity 27 (CAS CATO-C4X-340227)
- (3-Chlorophenyl)(3,4-difluorobenzyl)sulfane (CAS 1443312-92-2)
- Diethylene Glycol Dimethacrylate (CAS 2358-84-1)
- 8-(Methylsulfonyl)-1-oxa-4-thia-8-azaspiro[4.5]decane (CAS 1351601-18-7)
- 7-Chlorobenzo[d]thiazole (CAS 2942-09-8)
- 6-Bromo-4-(difluoromethyl)-5-iodopicolinaldehyde (CAS 1805414-22-5)
- 1-Morpholino-2-((4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl)thio)ethan-1-one (CAS 493017-61-1)
- [y-Glu15]-Semaglutide Impurity 134 (CAS CATO-C4X-2226134)
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