Nitrazepam EP Impurity A CAS 36020-93-6
| CAS No. | 36020-93-6 |
| Molecular Formula | C15H11N3O3 |
| Molecular Weight | 281.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Nitrazepam EP Impurity A (CAS 36020-93-6) is a certified pharmaceutical impurity reference standard with the molecular formula C15H11N3O3 and a molecular weight of 281.27 g/mol.
Structurally, Nitrazepam EP Impurity A (C15H11N3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 281.27 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Nitrazepam EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H11N3O3 |
| Molecular Weight | 281.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 3 |
Related Nitrazepam Standards
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- 2-(4-Bromo-3-fluorophenyl)-2-methylpropanenitrile (CAS 1027087-75-7)
- 4-Chloro-1-methyl-3-phenyl-1H-pyrazole-5-carboxylic acid (CAS 1245275-74-4)
- Liraglutide Impurity 22 (CAS 536721-25-2)
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