2-Bromo-3,4-difluorophenol CAS 1376335-05-5
| CAS No. | 1376335-05-5 |
| Molecular Formula | C6H3BrF2O |
| Molecular Weight | 208.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Bromo-3,4-difluorophenol (CAS 1376335-05-5), a certified reference material (molecular formula C6H3BrF2O, MW 208.99 g/mol) for analytical method development and quality control.
2-Bromo-3,4-difluorophenol (C6H3BrF2O) contains a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H3BrF2O |
| Molecular Weight | 208.99 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 4-Bromo-2,6-difluorophenol (CAS 104197-13-9)
- 2-Bromo-3,6-difluorophenol (CAS 1208077-18-2)
- (Z)-3-bromo-4-methoxy-4-oxobut-2-enoic acid (CAS 122457-36-7)
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- 4-Bromo-3,5-difluorophenol (CAS 130191-91-2)
- 4-Bromo-2,3-difluorophenol (CAS 144292-32-0)
- 3-Bromo-2,4-difluorophenol (CAS 1541784-30-8)
- 4-Bromo-6-(difluoromethyl)pyrimidine (CAS 1706448-11-4)
Recommended Standards
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- Prop-2-yn-1-yl 3-chloro-4-((4-methylbenzyl)oxy)benzoate (CAS 1706428-83-2)
- Allisartan Isoproxil Impurity 13 (CAS CATO-C4X-321713)
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- 3,7-Dimethyl-4,7-dihydropyrazolo[4,3-d][1,3]oxazin-5(1H)-one (CAS 72499-49-1)
- 4-((4-Chloro-1H-pyrazol-1-yl)methyl)thiophene-2-carbaldehyde (CAS 1006493-41-9)
- Tau Peptide (307-321) trifluoroacetate salt (CAS 330456-50-3)
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