4-Bromo-3,5-difluorophenol CAS 130191-91-2
| CAS No. | 130191-91-2 |
| Molecular Formula | C6H3BrF2O |
| Molecular Weight | 208.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Bromo-3,5-difluorophenol (CAS 130191-91-2), molecular formula C6H3BrF2O and molecular weight 208.99 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Bromo-3,5-difluorophenol (C6H3BrF2O) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Bromo-3,5-difluorophenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H3BrF2O |
| Molecular Weight | 208.99 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 4-Bromo-2,6-difluorophenol (CAS 104197-13-9)
- 2-Bromo-3,6-difluorophenol (CAS 1208077-18-2)
- (Z)-3-bromo-4-methoxy-4-oxobut-2-enoic acid (CAS 122457-36-7)
- 5-Bromo-3,6-difluoropyridin-2-amine (CAS 1267856-70-1)
- 2-Bromo-3,4-difluorophenol (CAS 1376335-05-5)
- 4-Bromo-2,3-difluorophenol (CAS 144292-32-0)
- 3-Bromo-2,4-difluorophenol (CAS 1541784-30-8)
- 4-Bromo-6-(difluoromethyl)pyrimidine (CAS 1706448-11-4)
Recommended Standards
- 1-Propanesulfonic acid, 3-bromo-, lithium salt (1:1) (CAS 127666-86-8)
- 4,6-Dichloro-5-nitropyrimidin-2-amine (CAS 134716-82-8)
- 5-Iodo-3-methyl-1,2-oxazole (CAS 126085-92-5)
- 3-Iodo-4-methyl-4H-1,2,4-triazole (CAS 1528684-35-6)
- 2-(5,7-Difluoro-1H-indazol-3-yl)acetic acid (CAS 944904-63-6)
- 2-Oxo-1,2-dihydropyridine-3-carbohydrazide (CAS 153336-74-4)
- Ochromycinone (CAS 28882-53-3)
- N-(5-Bromothiazol-2-yl)benzamide (CAS 29230-20-4)
- (1-Benzyl-7-chloro-5-iodo-3-methyl-2,3-dihydro-1H-pyrrolo[2,3-c]pyridin-3-yl)methanol (CAS 2639205-87-9)
- 3-amino-2-[(4-fluoro-2-methylphenyl)methyl]-N-methylpropanamide hydrochloride (CAS 1909336-88-4)
- 8-chloro-2-(methylsulfanyl)pyrido[3,4-d]pyrimidine (CAS 1578245-95-0)
- 2-(Benzo[b]thiophen-2-yl)ethanol (CAS 30962-69-7)
- 2-((4-(Trifluoromethyl)pyrimidin-2-yl)amino)butan-1-ol (CAS 1340428-97-8)
- Peptide Impurity 24 (CAS CATO-CPTD788824)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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