3-((4-(3-(Trifluoromethyl)phenoxy)piperidin-1-yl)methyl)pyrrolidin-3-ol CAS 1378017-05-0
| CAS No. | 1378017-05-0 |
| Molecular Formula | C17H23F3N2O2 |
| Molecular Weight | 344.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-((4-(3-(Trifluoromethyl)phenoxy)piperidin-1-yl)methyl)pyrrolidin-3-ol is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-((4-(3-(Trifluoromethyl)phenoxy)piperidin-1-yl)methyl)pyrrolidin-3-ol (CAS 1378017-05-0) is a high-purity analytical reference standard with the molecular formula C17H23F3N2O2 and a molecular weight of 344.37 g/mol.
Structurally, 3-((4-(3-(Trifluoromethyl)phenoxy)piperidin-1-yl)methyl)pyrrolidin-3-ol (C17H23F3N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 344.37 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-((4-(3-(Trifluoromethyl)phenoxy)piperidin-1-yl)methyl)pyrrolidin-3-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H23F3N2O2 |
| Molecular Weight | 344.37 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- 1-(2-(4-Methyl-6-(trifluoromethyl)pyrimidin-2-yl)ethyl)-3-(thiophen-2-ylmethyl)urea (CAS 1396751-99-7)
- 3-(3-(Trifluoromethyl)benzyl)benzofuro[3,2-d]pyrimidin-4(3H)-one (CAS 849055-55-6)
- 2,4,6-Tris(trifluoromethyl)benzoyl chloride (CAS 135130-97-1)
- 3-[3,5-di(trifluoromethyl)phenyl]prop-2-ynyl 2-chloroacetate (CAS 680579-65-1)
- 2,8-Bis(trifluoromethyl)-4-bromoquinoline (CAS 35853-45-3)
- 3-[3,5-Bis(trifluoromethyl)phenyl]-5-chloro-1,2-oxazole-4-carbaldehyde (CAS 1354919-16-6)
- 2-[3-(Trifluoromethyl)phenylsulfonamido]benzoic Acid (CAS 306955-85-1)
- 3-((3-(Trifluoromethyl)phenyl)sulfonamido)benzoic acid (CAS 613657-60-6)
Recommended Standards
- 4-{6-[(2-Pyridinylmethyl)amino]-1H-pyrrolo[2,3-b]pyridin-4-yl}benzoic acid (CAS 1377872-06-4)
- 2-(2-(((4-Aminopyridin-3-yl)amino)methyl)phenyl)isoindoline-1,3-dione (CAS 1417793-22-6)
- 6-((3-(tert-Butoxy)-3-oxopropyl)amino)-2-(pyridin-2-yl)pyrimidine-4-carboxylic acid (CAS 1373424-19-1)
- tert-Butyl 4-amino-4-[4-(trifluoromethyl)phenyl]piperidine-1-carboxylate (CAS 1707575-95-8)
- 3-Amino Lidocaine (CAS 39942-50-2)
- (S)-2-(((Benzyloxy)carbonyl)amino)-3-(methylamino)propanoic acid (CAS 160885-20-1)
- Felbamate-d4 (CAS 106817-52-1)
- 3-(4-(Trifluoromethyl)phenyl)propan-1-amine (CAS 101488-60-2)
- N-(3-Hydroxy-4-(hydroxymethyl)cyclopentyl)butyramide (CAS 1421513-27-0)
- 1-(2-aminoethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile hydrochloride (CAS 2044714-04-5)
- 3-Aminoheptan-1-ol (CAS 119910-50-8)
- 4-[2-[4-[2-methoxy-5-[2-(1-methylquinolin-1-ium-4-yl)ethyl]phenoxy]phenyl]ethyl]-1-methyl-quinolin-1-ium diiodide (CAS 365542-47-8)
- (inh)-172 3-[(3-trifluoromethyl)phenyl]-5-[(3-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone 307510-92-5 4-({4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl)benzoic acid 5-[(4-carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl]-4-thiazolidinone CFTR(inh)-172 CFTRinh-172 CHEBI:131686 Cystic fibrosis transmembrane conductance regulator inhibitor CFTR(inh)-172 cystic fibrosis transmembrane regulator inhibitor 172 (CAS 307510-92-5)
- Des-Ala28-Tirzepatide (CAS CATO-CPTD788945)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com