(inh)-172 3-[(3-trifluoromethyl)phenyl]-5-[(3-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone 307510-92-5 4-({4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl)benzoic acid 5-[(4-carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl]-4-thiazolidinone CFTR(inh)-172 CFTRinh-172 CHEBI:131686 Cystic fibrosis transmembrane conductance regulator inhibitor CFTR(inh)-172 cystic fibrosis transmembrane regulator inhibitor 172 CAS 307510-92-5
| CAS No. | 307510-92-5 |
| Molecular Formula | C18H10F3NO3S2 |
| Molecular Weight | 409.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(inh)-172 3-[(3-trifluoromethyl)phenyl]-5-[(3-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone 307510-92-5 4-({4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl)benzoic acid 5-[(4-carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl]-4-thiazolidinone CFTR(inh)-172 CFTRinh-172 CHEBI:131686 Cystic fibrosis transmembrane conductance regulator inhibitor CFTR(inh)-172 cystic fibrosis transmembrane regulator inhibitor 172 (CAS 307510-92-5), molecular formula C18H10F3NO3S2 and molecular weight 409.40 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C18H10F3NO3S2, (inh)-172 3-[(3-trifluoromethyl)phenyl]-5-[(3-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone 307510-92-5 4-({4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl)benzoic acid 5-[(4-carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl]-4-thiazolidinone CFTR(inh)-172 CFTRinh-172 CHEBI:131686 Cystic fibrosis transmembrane conductance regulator inhibitor CFTR(inh)-172 cystic fibrosis transmembrane regulator inhibitor 172 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 409.40 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (inh)-172 3-[(3-trifluoromethyl)phenyl]-5-[(3-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone 307510-92-5 4-({4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl)benzoic acid 5-[(4-carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl]-4-thiazolidinone CFTR(inh)-172 CFTRinh-172 CHEBI:131686 Cystic fibrosis transmembrane conductance regulator inhibitor CFTR(inh)-172 cystic fibrosis transmembrane regulator inhibitor 172 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H10F3NO3S2 |
| Molecular Weight | 409.40 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related inh Standards
- 1-(3,5-Bis(trifluoromethyl)phenyl)-4-(pyridin-4-yl)-1H-[1,2,3]triazolo[4,5-c]pyridine (CAS 439093-64-8)
- 5,7-bis(trifluoromethyl)[1,8]naphthyridin-2-yl 4-chlorophenyl sulfide (CAS 241488-33-5)
- 3-{5-[3,5-di(trifluoromethyl)phenyl]-2-furyl}-1-phenylprop-2-en-1-one (CAS 646497-84-9)
- 3-(((3-(Trifluoromethyl)benzyl)thio)methyl)-2,3-dihydro-5H-thiazolo[2,3-b]quinazolin-5-one (CAS 477860-29-0)
- 2-[(2-{2-methyl-4-[5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl]anilino}-2-oxoethyl)thio]pyridinium-1-olate (CAS 299207-98-0)
- alpha-(Trifluoromethyl)-1-trityl-1H-imidazole-4-methanol (CAS 1346809-22-0)
- Ethyl 2-({3-[2-(trifluoromethyl)benzenesulfonamido]-1H-1,2,4-triazol-5-yl}sulfanyl)acetate (CAS 866010-91-5)
- 2-((4-Phenyl-5-((3-(trifluoromethyl)phenoxy)methyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 383145-84-4)
Recommended Standards
- N-[3-(Morpholin-4-yl)propyl]-4-[3-(trifluoromethyl)benzoyl]-1H-pyrrole-2-carboxamide (CAS 439111-17-8)
- N,N-Dinitroso Valsartan Desvaleryl Impurity 86 (CAS CATO-C4X-105786)
- N-(4-fluorophenyl)-1,3-dimethyl-5-((3-(trifluoromethyl)phenyl)thio)-1H-pyrazole-4-carboxamide (CAS 303997-97-9)
- Fluoxetine Impurity 19 (CAS 1026723-45-4)
- N-(4-chlorophenyl)-2,8-dimethylimidazo[1,2-a]pyridine-3-carboxamide (CAS 241146-69-0)
- Papyriferic Acid (CAS 78782-15-7)
- 2-(5-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-7-yl)acetic acid (CAS 1391733-25-7)
- 1-Ethyl-4-((4-nitrophenoxy)methyl)-1H-pyrazole (CAS 1260379-24-5)
- 4-(4-Propylphenyl)butanoic acid (CAS 25711-53-9)
- Dicyclohexyl[3-methoxy-2′,4′,6′-tris(1-methylethyl)[1,1′-biphenyl]-2-yl]phosphine (CAS 2118959-59-2)
- 5-Hexyl-2,4-dihydroxybenzaldehyde (CAS 37470-87-4)
- Ethyl 7-oxo-3-azabicyclo[3.3.1]Nonane-3-carboxylate (CAS 850991-62-7)
- Ethyl 4-fluoro-2-methoxy-3-methylbenzoate (CAS 2114099-46-4)
- Peptide Impurity 81 TFA (CAS CATO-CPTD788581)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com