5-Chloro-7-fluoro-3,4-dihydro-2h-1,4-benzothiazine CAS 1378508-59-8
| CAS No. | 1378508-59-8 |
| Molecular Formula | C8H7ClFNS |
| Molecular Weight | 203.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-7-fluoro-3,4-dihydro-2h-1,4-benzothiazine (C8H7ClFNS) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
5-Chloro-7-fluoro-3,4-dihydro-2h-1,4-benzothiazine (CAS 1378508-59-8), molecular formula C8H7ClFNS and molecular weight 203.66 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-7-fluoro-3,4-dihydro-2h-1,4-benzothiazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7ClFNS |
| Molecular Weight | 203.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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- 4-{[(dimethylsulfamoyl)amino]methyl}-2-[2-(pyrrolidin-1-yl)ethyl]-1,2-dihydrophthalazin-1-one (CAS 1448071-38-2)
- Ezetimibe Impurity 119 (CAS 914777-32-5)
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- 3-Bromo-2-(cyclopentyloxy)pyridine (CAS 1247429-75-9)
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- D-Tyr10-Tirzepatide (CAS CATO-CPTD788922)
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