5-amino-2-chloro-4-hydroxybenzonitrile CAS 1378583-39-1
| CAS No. | 1378583-39-1 |
| Molecular Formula | C7H5ClN2O |
| Molecular Weight | 168.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 5-amino-2-chloro-4-hydroxybenzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
5-amino-2-chloro-4-hydroxybenzonitrile (CAS 1378583-39-1), molecular formula C7H5ClN2O and molecular weight 168.58 g/mol, is a CATO reference standard with documented purity and traceability.
5-amino-2-chloro-4-hydroxybenzonitrile (C7H5ClN2O) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H5ClN2O |
| Molecular Weight | 168.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related amino Standards
- 2-Amino-7-chloro-[1,2,4]triazolo[1,5-a]pyridine (CAS 1131410-85-9)
- 2-Amino-6-chloro-[1,2,4]triazolo[1,5-a]pyridine (CAS 1239647-60-9)
- 2-Amino-8-chloro-[1,2,4]triazolo[1,5-a]pyridine (CAS 1245644-68-1)
- 7-Amino-2-chlorofuro[2,3-c]pyridine (CAS 1326713-69-2)
- 3-Amino-6-chloroimidazo[1,2-b]pyridazine (CAS 166176-45-0)
- 2-Amino-5-chloro-[1,2,4]triazolo[1,5-a]pyridine (CAS 175965-64-7)
- 2-Amino-4-chloro-6-methylpyrimidine-5-carbonitrile (CAS 99586-66-0)
- 2-Amino-4-chloro-7H-pyrrolo[2,3-d]pyrimidine (CAS 84955-31-7)
Recommended Standards
- 5-Chloro-1H-pyrrolo[2,3-c]pyridin-2(3H)-one (CAS 136888-17-0)
- 5-Chloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidine (CAS 1393181-01-5)
- 6-Chloro-4-azaindoline-2-one (CAS 136888-12-5)
- 6-Chloro-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one (CAS 1393540-02-7)
- 5-(trifluoromethyl)isoquinoline (CAS 120568-09-4)
- 6-Bromo-2-(difluoromethyl)benzo[d]thiazole (CAS 1644664-05-0)
- 1-Benzhydrylazetidine-3-carbaldehyde (CAS 72351-37-2)
- N-Isopropyl-2-methyl-d3-2-propyl-3-hydroxypropyl Carbamate (CAS 1189878-05-4)
- 2-Amino-1,5-dimethylbenzimidazole (CAS 39860-12-3)
- 2-(5-Methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)ethyl 4-methylbenzoate (CAS 865658-46-4)
- 3-(2-Chloroethyl)oxolane-3-carboxylic acid (CAS 1866638-98-3)
- rac-Bunolol HCl (CAS 31969-05-8)
- Benzyl (6-bromopyridin-3-yl)carbamate (CAS 175393-05-2)
- Peptide 431 (CAS CATO-CPTD788431)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com