5-Chloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidine CAS 1393181-01-5

Description

The occurrence of 5-Chloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidine is closely related to a nitrile group, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 5-Chloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidine (CAS 1393181-01-5), a certified reference material (molecular formula C6H5ClN4, MW 168.58 g/mol) for analytical method development and quality control.

The molecular framework of 5-Chloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidine (C6H5ClN4) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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