Ilaprazole Impurity 73 CAS 1378653-43-0
| CAS No. | 1378653-43-0 |
| Molecular Formula | C8H10ClNO |
| Molecular Weight | 171.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ilaprazole Impurity 73 (C8H10ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Ilaprazole Impurity 73 (CAS 1378653-43-0) is a certified pharmaceutical impurity reference standard with the molecular formula C8H10ClNO and a molecular weight of 171.62 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ilaprazole Impurity 73 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10ClNO |
| Molecular Weight | 171.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ilaprazole Standards
- Ilaprazole Impurity 72 (CAS 1256807-19-8)
- Ilaprazole Impurity 74 (CAS 1807231-85-1)
- Ilaprazole Impurity 141 (CAS CATO-C4X-1130141)
- Ilaprazole Impurity 214 (CAS 172152-60-2)
- Ilaprazole Impurity 43 (CAS CATO-C4X-113043)
- Ilaprazole Impurity 226 (CAS 116419-12-6)
- Ilaprazole Impurity 42 (CAS 2288740-67-8)
- Ilaprazole Impurity 234 (CAS CATO-C4X-1130234)
Recommended Standards
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- 1007-55-2 6-Chloro-N-isopropylpyridazin-3-amine 7262AC C7H10ClN3 (CAS 1007-55-2)
- Orforglipron Impurity 46 (CAS CATO-C4X-323446)
- Alectinib Impurity 51 (CAS CATO-C4X-283651)
- Gefapixant Impurity 6 (CAS CATO-C4X-28496)
- 2-(4-(Difluoromethyl)-5-hydroxy-6-iodopyridin-3-yl)acetonitrile (CAS 1805535-09-4)
- Ammonium 4,5-dioxidobenzene-1,3-disulfonate (CAS 1159824-56-2)
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- 2-(5-BRomo-2-methyl-1h-indol-3-yl)ethanamine, HCl (CAS 478914-87-3)
- (2-(7-Oxabicyclo[4.1.0]Heptan-3-yl)ethyl)dimethoxy(methyl)silane (CAS 97802-57-8)
- 2-Chloro-5-(methylthio)-3-(trifluoromethyl)pyridine (CAS 1820650-15-4)
- [Glu]17-Semaglutide (CAS CATO-CPTD788604)
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