2-(1-(2,2,2-Trifluoroacetamido)cyclohexyl)acetic acid CAS 1379012-17-5
| CAS No. | 1379012-17-5 |
| Molecular Formula | C10H14F3NO3 |
| Molecular Weight | 253.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(1-(2,2,2-Trifluoroacetamido)cyclohexyl)acetic acid (CAS 1379012-17-5) is a high-purity analytical reference standard with the molecular formula C10H14F3NO3 and a molecular weight of 253.22 g/mol.
The molecular framework of 2-(1-(2,2,2-Trifluoroacetamido)cyclohexyl)acetic acid (C10H14F3NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14F3NO3 |
| Molecular Weight | 253.22 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoroacetamido Standards
- 1-(2,2,2-Trifluoroacetamido)cycloheptane-1-carboxylic acid (CAS 1099040-65-9)
- 4-Methyl-1-(2,2,2-trifluoroacetamido)cyclohexane-1-carboxylic acid (CAS 1099078-56-4)
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