4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-(hydroxymethyl)picolinamide CAS 1380310-94-0
| CAS No. | 1380310-94-0 |
| Molecular Formula | C21H16ClF3N4O4 |
| Molecular Weight | 480.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-(hydroxymethyl)picolinamide (C21H16ClF3N4O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-(hydroxymethyl)picolinamide (CAS 1380310-94-0), a certified reference material (molecular formula C21H16ClF3N4O4, MW 480.82 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-(hydroxymethyl)picolinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H16ClF3N4O4 |
| Molecular Weight | 480.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 4-[[9-chloro-7-(2,6-difluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2,3,5,6-tetradeuteriobenzoic acid (CAS 1346600-37-0)
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Recommended Standards
- (2Z)-2-(4-Bromobenzenesulfonyl)-3-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]prop-2-enenitrile (CAS 1025666-41-4)
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- Ethyl N-((4-chlorophenyl)sulfonyl)-N-(2,4-dichloro-5-isopropoxyphenyl)glycinate (CAS 338961-79-8)
- Myristyl stearate (CAS 17661-50-6)
- ({[(4-fluorophenyl)sulfonyl]amino}oxy)acetic acid (CAS 790725-72-3)
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- 3,5-Dimethylisoxazol-4-yl 2-benzyl-3,3,3-trifluoropropanoate (CAS 959265-34-0)
- Anastrozole Impurity 2 (CAS 120512-36-9)
- 2-(N-benzylphenylsulfonamido)benzoic acid (CAS 401602-98-0)
- 2-Fluoro-4-hydroxy-5-nitrobenzenemethanol (CAS 1823330-91-1)
- N1-cyclopropyl-3-methylbenzene-1,4-diamine (CAS 170693-34-2)
- 2-[4-(3-oxobutyl)phenoxy]propanoic acid (CAS 926206-54-4)
- 3-(5-(4-Bromophenyl)furan-2-yl)-2-(furan-2-ylsulfonyl)acrylonitrile (CAS 853407-08-6)
- Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 75976-10-2)
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