1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid CAS 138059-98-0
| CAS No. | 138059-98-0 |
| Molecular Formula | C18H17F4N3O3 |
| Molecular Weight | 399.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 138059-98-0), a certified reference material (molecular formula C18H17F4N3O3, MW 399.34 g/mol) for analytical method development and quality control.
1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid (C18H17F4N3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H17F4N3O3 |
| Molecular Weight | 399.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Cyclopropyl Standards
- (5-Cyclopropyl-isoxazol-4-yl)-(4-ethanesulfonyl-2,5-dimethyl-3-oxazol-2-yl-phenyl)-methanone (CAS 1231571-57-5)
- (5-Cyclopropyl-isoxazol-4-yl)-(3-ethanesulfonyl-2,5-dimethyl-4-oxazol-2-yl-phenyl)-methanone (CAS 1231596-90-9)
- 2-((4-Benzyl-5-cyclopropyl-4H-1,2,4-triazol-3-yl)thio)-1-(5-fluoro-2-methoxyphenyl)ethan-1-one (CAS 919901-13-6)
- 9-Cyclopropyl-6-fluoro-8-methoxy-7-(2-methylpyridin-4-yl)isothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione (CAS 906527-41-1)
- methyl 3-cyclopropyl-1-(4-fluorophenyl)-6-(4-methylphenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011396-58-9)
- N-Cyclopropyl-2,4-difluoro-5-(((2-(pyridin-2-ylamino)thiazol-5-yl)methyl)amino)benzamide (CAS 639858-32-5)
- (1-((3-Cyclopropyl-1,2,4-oxadiazol-5-yl)methyl)-4,4-dioxido-1H-benzo[e][1,3,4]thiadiazin-3-yl)(pyrrolidin-1-yl)methanone (CAS 1251698-42-6)
- Cyclopropyl[4-(1-{[6-(trifluoromethyl)-3-pyridinyl]methyl}-4-piperidinyl)-1-piperazinyl]methanone (CAS 909670-30-0)
Recommended Standards
- Seviteronel R enantiomer (CAS 1375603-38-5)
- 3-(Furan-2-yl)-5-(1-((3-(trifluoromethyl)phenyl)sulfonyl)azetidin-3-yl)-1,2,4-oxadiazole (CAS 1428372-30-8)
- WAY-326100 (CAS 869714-20-5)
- 2-(2-{[3-Cyano-6-(5-methylfuran-2-yl)-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}acetamido)acetic acid (CAS 903086-53-3)
- 2-Fluoro-3-(trifluoromethyl)benzaldehyde 2-fluoro-3-trifluoromethyl-benzaldehyde 2-fluoro-3-trifluoromethylbenzaldehyde A, A, A,2-Tetrafluoro-M-tolualdehyde 112641-20-0 (CAS 112641-20-0)
- 3-Bromo-2-fluorophenylacetic Acid (CAS 1375964-39-8)
- 1,1'-Ethane-1,2-diylbis(5-oxopyrrolidine-3-carboxylic acid) (CAS 2761-13-9)
- 1-(Pyridin-4-yl)-2-azaspiro[3.3]Heptane (CAS 1869673-80-2)
- 6-(3-Methoxyphenyl)imidazo[1,2-b]pyridazin-2-amine (CAS 1191894-48-0)
- 3-Chloro-6-(p-tolyl)-4-(trifluoromethyl)pyridazine (CAS 1271475-96-7)
- N-(5-Methoxybenzofuran-3-yl)acetamide (CAS 64663-55-4)
- 4-(Methylsulfonyl)thiophene-2-sulfonyl chloride (CAS 1620572-54-4)
- 2-((2-Fluorophenyl)thio)cyclohexan-1-one (CAS 1044049-28-6)
- Anorexigenic Peptide (CAS 69275-10-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com