Ethyl 4-hydroxy-2-oxo-1-phenyl-1,2-dihydro-1,8-naphthyridine-3-carboxylate CAS 138305-20-1
| CAS No. | 138305-20-1 |
| Molecular Formula | C17H14N2O4 |
| Molecular Weight | 310.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Ethyl 4-hydroxy-2-oxo-1-phenyl-1,2-dihydro-1,8-naphthyridine-3-carboxylate (CAS 138305-20-1) is a high-purity analytical reference standard with the molecular formula C17H14N2O4 and a molecular weight of 310.30 g/mol.
The molecular framework of Ethyl 4-hydroxy-2-oxo-1-phenyl-1,2-dihydro-1,8-naphthyridine-3-carboxylate (C17H14N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H14N2O4 |
| Molecular Weight | 310.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- 6-Acetyl-7-hydroxy-2-(2-methoxyphenyl)-4H-chromen-4-one (CAS 126412-03-1)
- 5-Hydroxy-3-[2-(4-methoxy-phenyl)-2-oxo-ethylidene]-3,4-dihydro-1H-quinoxalin-2-one (CAS 1380572-52-0)
- 2-[(4-Hydroxy-3,5-dimethoxyphenyl)methylidene]-2,3-dihydro-1H-indene-1,3-dione (CAS 53566-07-7)
- 3-(2-(4-Hydroxy-3-methoxybenzylidene)hydrazinyl)quinoxalin-2(1H)-one (CAS 338757-81-6)
- 1-(2-Hydroxy-4-{[3-(trifluoromethyl)benzyl]oxy}phenyl)-1-ethanone (CAS 860611-86-5)
- 1-Hydroxy-2-isobutyl-8-methoxyanthracene-9,10-dione (CAS 139565-35-8)
- 2-Butyl-1-hydroxy-8-methoxyanthracene-9,10-dione (CAS 139582-75-5)
- 1-(6-Hydroxy-3-methoxy-2,4-dimethylphenyl)naphthalene-2,3-diol (CAS 1832513-68-4)
Recommended Standards
- Methyl 6-benzyl-4-hydroxy-5-oxo-5,6-dihydro-2,6-naphthyridine-3-carboxylate (CAS 1392839-33-6)
- 3-(3,5-Dimethylphenyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylic acid (CAS 1370594-84-5)
- (2R,3R,3aS,9aR)-3-Hydroxy-2-(((tetrahydro-2H-pyran-2-yl)oxy)methyl)-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one (CAS 157024-76-5)
- 8-Methoxy-3-(2-methoxybenzoyl)-2H-chromen-2-one (CAS 1351398-69-0)
- COD In Water (CAS CATO-CCRM106039)
- Scopoletin (CAS 92-61-5)
- 3-(2-Fluorophenoxy)-1-methyl-1H-pyrazol-4-amine hydrochloride (CAS 1431964-03-2)
- 4-Cyclopropoxy-N,N-dimethyl-6-(methylsulfonamido)picolinamide (CAS 1243347-05-8)
- {3-Fluoro-4-[(3-methyloxetan-3-yl)methoxy]phenyl}methanamine (CAS 1402232-71-6)
- Desacetyl Diltiazem (CAS 42399-40-6)
- 8-Methoxy-N-(4-methoxyphenyl)-2H-chromene-3-carboxamide (CAS 288861-42-7)
- 1-(Furan-3-yl)prop-2-en-1-one (CAS 96334-38-2)
- 1554618-31-3 Ethyl 1-(azidoacetyl)piperidine-4-carboxylate MFCD23696146 (CAS 1554618-31-3)
- Glucagon-like peptide 2 (CAS 89750-15-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com