(S)-3-(3-Chlorophenyl)pyrrolidine hydrochloride CAS 1384268-48-7
| CAS No. | 1384268-48-7 |
| Molecular Formula | C10H12ClN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (S)-3-(3-Chlorophenyl)pyrrolidine hydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(S)-3-(3-Chlorophenyl)pyrrolidine hydrochloride (CAS 1384268-48-7), molecular formula C10H12ClNHCl and molecular weight 218.12 g/mol, is a CATO reference standard with documented purity and traceability.
(S)-3-(3-Chlorophenyl)pyrrolidine hydrochloride (C10H12ClNHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12ClN HCl |
| Molecular Weight | 218.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related S Standards
- 2-(2-Chlorophenyl)-2-(pyrrolidin-1-yl)acetamide (CAS 1000340-02-2)
- N-(2-Chlorophenyl)-5-methyl-1-phenyl-1H-1,2,4-triazole-3-carboxamide (CAS 1000572-01-9)
- N-(2-Chlorophenyl)-5-oxo-1-(p-tolyl)-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000573-94-3)
- Methyl 1-(2-chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000576-85-1)
- 1-(4-Chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylic acid phenylamide (CAS 1000577-01-4)
- Benzyl 1-(4-chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000577-09-2)
- 1-(2-Chlorophenyl)-5-oxo-N-phenyl-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000577-29-6)
- 2-(2-Chlorophenyl)-1-phenylethan-1-amine (CAS 1000615-44-0)
Recommended Standards
- Methyl 2-[(chloroacetyl)amino]benzoate (CAS 58915-18-7)
- tert-Butyl [4-(2-fluorobenzyl)piperidin-4-yl]methylcarbamate (CAS 1713164-12-5)
- 1-(6-Bromocinnolin-3-yl)ethanone (CAS 1509900-01-9)
- Ethyl (1S,3S,6R)-7-oxabicyclo[4.1.0]heptane-3-carboxylate (CAS 365997-31-5)
- 1-(Allyloxymethyl)-2-fluorobenzene (CAS 1199773-12-0)
- rel-(3aR,4S,7R,7aS)-3a,4,7,7a-Tetrahydro-8-hydroxy-4,7-methanoisobenzofuran-1,3-dione (CAS 1815574-20-9)
- Tert-butyl 4-(2-bromo-4-nitrophenyl)piperazine-1-carboxylate (CAS 1163126-69-9)
- 2-Iodophenanthrene (CAS 55691-84-4)
- (R)-1-(6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethan-1-ol (CAS 2410619-06-4)
- Semaglutide impurity 50 (CAS 2773558-66-8)
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