Apremilast impurity 19 CAS 1384440-16-7
| CAS No. | 1384440-16-7 |
| Molecular Formula | C19H20N2O6S |
| Molecular Weight | 404.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Apremilast impurity 19 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Apremilast impurity 19 (CAS 1384440-16-7), a pharmacopoeial impurity reference standard (molecular formula C19H20N2O6S, MW 404.44 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Apremilast impurity 19 (C19H20N2O6S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C19H20N2O6S |
| Molecular Weight | 404.44 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Apremilast Standards
- Apremilast Impurity 35 (CAS 253168-83-1)
- Apremilast Impurity 54 (CAS CATO-C4X-100954)
- Apremilast impurity 18 (CAS 1384439-79-5)
- Apremilast Impurity 2 (CAS 635705-72-5)
- Apremilast Impurity 39 (CAS CATO-C4X-100939)
- Apremilast Impurity 99 (CAS CATO-C4X-100999)
- Apremilast Impurity 117 (CAS CATO-C4X-1009117)
- Apremilast Impurity 37 (CAS 1407140-51-5)
Recommended Standards
- Z-Met-ONp (CAS 2483-42-3)
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- Ceftibuten Impurity 1 (CAS CATO-C4X-18901)
- Indocyanine Green Impurity 1 (CAS CATO-C4X-25031)
- Sugammadex Sodium Impurity 54 (CAS CATO-C4X-190654)
- Desmopressin Impurity 31 (CAS CATO-C4X-221531)
- 2-(2,4,6-Trichloropyrimidin-5-yl)ethanol (CAS 219312-97-7)
- 1-Nitropropane (CAS 108-03-2)
- Piperazine-1-carboxylic acid (3-chlorophenyl)-amide hydrochloride (CAS 1170255-29-4)
- 2-(3-Pyrazin-2-yl-propyl)-azetidine-2-carboxylic aciddimethylamide trifluoroacetic acid salt (CAS 1361118-57-1)
- N-(3-chloro-2-methylphenyl)-N-(phenylsulfonyl)glycine (CAS 491843-94-8)
- Sitaxsentan (CAS 184036-34-8)
- Biotinyl-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 213779-13-6)
Why CATO?
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