5,8-Difluoro-1,2,3,4-tetrahydroquinoline hydrochloride CAS 1384677-35-3
| CAS No. | 1384677-35-3 |
| Molecular Formula | C9H9F2N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5,8-Difluoro-1,2,3,4-tetrahydroquinoline hydrochloride.
5,8-Difluoro-1,2,3,4-tetrahydroquinoline hydrochloride (CAS 1384677-35-3), molecular formula C9H9F2NHCl and molecular weight 205.63 g/mol, is a CATO reference standard with documented purity and traceability.
5,8-Difluoro-1,2,3,4-tetrahydroquinoline hydrochloride (C9H9F2NHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5,8-Difluoro-1,2,3,4-tetrahydroquinoline hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9F2N HCl |
| Molecular Weight | 205.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 2-(4,5-Difluoro-2-nitrophenyl)acetic acid (CAS 1000339-22-9)
- 1-[6,8-Difluoro-2-(trifluoromethyl)quinol-4-yl]piperazine (CAS 1000339-47-8)
- 1-[6,8-Difluoro-2-(trifluoromethyl)quinol-4-yl]homopiperazine (CAS 1000339-49-0)
- 4,7-Difluoro-1H-indazole (CAS 1000341-68-3)
- 5,7-Difluoro-2H-indazole-3-carbaldehyde (CAS 1000343-25-8)
- 6,7-Difluoro-1H-indazol-3-ol (CAS 1000343-93-0)
- 2-(3,5-Difluoro-2-pyridyl)acetic acid (CAS 1000518-01-3)
- 2-(2,4-Difluoro-3-methylphenyl)acetic acid (CAS 1000545-11-8)
Recommended Standards
- 2-(Bromomethyl)-4-(difluoromethyl)-3-iodo-6-(trifluoromethyl)pyridine (CAS 1806992-09-5)
- (S)-[1,1'-Binaphthalene]-2,2'-dicarbonitrile (CAS 129783-81-9)
- (12a,18a)-5,6,12,12a,13,18,18a,19-Octahydro-5,6-dimethyl-13,18[1',2']-benzenobisbenzimidazo [1,2-b:2',1'-d]benzo[i][2.5]benzodiazocine potassium trifl (CAS 958004-04-1)
- 3-(3,4-Diethoxybenzylidene)-5-methyldihydrofuran-2(3H)-one (CAS 93159-61-6)
- 2-(4-Piperidyloxy)pyridine (CAS 127806-46-6)
- N,2,2-trimethylcyclopropan-1-amine hydrochloride (CAS 1795279-04-7)
- Ezetimibe Impurity 109 (CAS CATO-C4X-1098109)
- Orforglipron Impurity 11 (CAS 2212022-56-3)
- Acid Green 1 ( Product) (CAS 19381-50-1)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
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