Orforglipron Impurity 11 CAS 2212022-56-3
| CAS No. | 2212022-56-3 |
| Molecular Formula | C26H25F2N7O |
| Molecular Weight | 489.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Orforglipron Impurity 11 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 489.52 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Orforglipron Impurity 11 (CAS 2212022-56-3) is a certified pharmaceutical impurity reference standard with the molecular formula C26H25F2N7O and a molecular weight of 489.52 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H25F2N7O |
| Molecular Weight | 489.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 7 |
Related Orforglipron Standards
- Orforglipron Impurity 18 (CAS CATO-C4X-323418)
- Orforglipron impurity 20 (CAS CATO-C4X-323420)
- Orforglipron impurity 66 (CAS CATO-C4X-323466)
- Orforglipron Impurity 138 (CAS CATO-C4X-3234138)
- Orforglipron Impurity 104 (CAS CATO-C4X-3234104)
- Orforglipron Impurity 107 (CAS CATO-C4X-3234107)
- Orforglipron Impurity 114 (CAS CATO-C4X-3234114)
- Orforglipron impurity 70 (CAS CATO-C4X-323470)
Recommended Standards
- Benidipine Impurity 26 (CAS CATO-C4X-112026)
- Ethyl 3-[(2-benzoyl-1-benzofuran-3-yl)methoxy]pyrido[1,2-a]indole-10-carboxylate (CAS 478067-91-3)
- D-luciferin1-(4,5-dimethoxy-2-nitrophenyl)ethylester (CAS 223920-67-0)
- 3-(Benzo[d][1,3]dioxol-5-yl)-4-(2-hydroxyethyl)-6,7-dimethoxy-2-(4-methoxybenzyl)isoquinolin-1(2H)-one (CAS 2248702-75-0)
- Tadalafil Impurity 131 (CAS 209120-51-4)
- Nifekalant impurity 3 (CAS CATO-C4X-27973)
- Carebastine Impurity 2 (CAS 2626068-21-9)
- 2,6-Dimethoxyanthracene-9,10-dione (CAS 963-96-2)
- 6-Chloro-N-(3,5-difluorophenyl)pyridine-2-carboxamide (CAS 866043-16-5)
- tert-Butyl 2-isopropylpiperazine-1-carboxylate hydrochloride (CAS 1203011-26-0)
- N-(piperidin-1-ylsulfonyl)-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide (CAS 866157-40-6)
- Ethyl 4-(chlorosulphonyl)-1,2-diphenyl-5-methyl-1H-pyrrole-3-carboxylate, tech (CAS 1065103-48-1)
- 1-(2,4-Dichlorophenyl)-2-(pyridin-3-yl)ethanone (CAS 83227-42-3)
- (Asp28)-Exenatide trifluoroacetate salt (CAS 1678417-24-7)
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